merck millipore,默克密理愽
  • merck millipore,默克密理博,218696,Casein Kinase I Inhibitor, D4476 - CAS 301836-43-1 - Calbiochem

  • merck millipore,默克密理博,218696,Casein Kinase I Inhibitor, D4476 - CAS 301836-43-1 - Calbiochem

    产品名称：Casein Kinase I Inhibitor, D4476 - CAS 301836-43-1 - Calbiochem
    产品型号：218696
    The Casein Kinase I Inhibitor, D4476, also referenced under CAS 301836-43-1, controls the biological activity of Casein Kinase I. This small molecule/inhibitor is primarily used for Phosphorylation &  More>>

    merck millipore,默克密理博,218696,Casein Kinase I Inhibitor, D4476 - CAS 301836-43-1 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,218696,Casein Kinase I Inhibitor, D4476 - CAS 301836-43-1 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₂₃H₁₈N₄O₃301836-43-1
    描述
    概述 A cell-permeable triaryl substituted imidazolo compound that acts as a potent, reversible and relatively specific ATP-competitive inhibitor of CK1 (IC50 = 0.2 µM from S. pombe; 0.3 µM for CK1δ) and ALK5 (IC50 = 0.5 µM). A weak inhibitor of p38α MAP kinase (IC50 = 12 µM) and only weakly affects the activities of a panel of kinases tested, including PKB, SGK and GSK-3β. Suppresses the site-specific phosphorylation (Ser322 and Ser325) and nuclear exclusion of FOXO1a in H4IIE hepatoma cells. Shown to be ~10-fold more potent than IC261 (Cat. No. 400090; IC50 = 2.5 µM for CK1).
    产品目录编号 218696
    品牌系列 Calbiochem®
    同义词 CK1 Inhibitor, 4-(4-(2,3-Dihydrobenzo[1,4]dioxin-6-yl)-5-pyridin-2-yl-1H-imidazol-2-yl)benzamide
    参考
    参考 Rena, G., et al. 2004. EMBO Reports 5, 60.
    产品信息
    CAS号 301836-43-1
    具有ATP竞争性 Y
    形式 Crystalline solid
    Hill配方 C₂₃H₁₈N₄O₃
    化学配方 C₂₃H₁₈N₄O₃
    Molar Mass 398.4
    可逆 Y
    结构配方图像
    生物信息
    主靶 CK1, CK1d
    主靶IC50 0.2 µM against CK1 from S. pombe; 0.3 µM for CK1δ 0.5 µM against ALK5
    纯度 ≥95% by HPLC
    理化信息
    细胞可渗透 Y
    溶解度 DMSO
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 +2°C to +8°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,218696,Casein Kinase I Inhibitor, D4476 - CAS 301836-43-1 - Calbiochem

上一件merck millipore产品：merck millipore,默克密理博,529573,PP2 - CAS 172889-27-9 - Calbiochem
下一件merck millipore产品：merck millipore,默克密理博,06-248,Anti-IRS1 Antibody


相关产品

merck millipore,默克密理博,ABE391,Anti-RPS3 Antibody merck millipore,默克密理博,ABE391,Anti-RPS3 Antibody

merck millipore,默克密理博,SF-1191,LRRK2; Human, Cyanine 5 RNA Detection Probe,SmartFlare merck millipore,默克密理博,SF-1191,LRRK2; Human, Cyanine 5 RNA Detection Probe,SmartFlare

merck millipore,默克密理博,MAB10765,Anti-Red Fluorescent Protein Antibody, clone 1DS-1A6,MAB10765 merck millipore,默克密理博,MAB10765,Anti-Red Fluorescent Protein Antibody, clone 1DS-1A6,MAB10765

merck millipore,默克密理博,05-1341,Anti-Histone H3 Antibody, (Unmodified Lys4), clone CMA301 merck millipore,默克密理博,05-1341,Anti-Histone H3 Antibody, (Unmodified Lys4), clone CMA301

merck millipore,默克密理博,529573,PP2 - CAS 172889-27-9 - Calbiochem merck millipore,默克密理博,529573,PP2 - CAS 172889-27-9 - Calbiochem

merck millipore,默克密理博,06-248,Anti-IRS1 Antibody merck millipore,默克密理博,06-248,Anti-IRS1 Antibody

merck millipore,默克密理博,575143,PhosphoDetect™ Anti-STAT6 (pTyr⁶⁴¹) Rabbit pAb merck millipore,默克密理博,575143,PhosphoDetect™ Anti-STAT6 (pTyr⁶⁴¹) Rabbit pAb

merck millipore,默克密理博,14-535M,Rse Protein, active, 250 µg merck millipore,默克密理博,14-535M,Rse Protein, active, 250 µg

merck millipore,默克密理博,580566,Tenovin-1 - CAS 380315-80-0 - Calbiochem merck millipore,默克密理博,580566,Tenovin-1 - CAS 380315-80-0 - Calbiochem

merck millipore,默克密理博,AB9830-50UL,Anti-K2P4.1 Antibody merck millipore,默克密理博,AB9830-50UL,Anti-K2P4.1 Antibody


whatman,沃特曼,nalgene,耐洁,merck millipore,默克密理愽,sartorius,赛多利斯,pall,颇尔
thermo fisher,赛默飞世尔,GE,MN,macherey-nagel,advantec,wheaton,brand,普兰德,welch,airtech


上海羽令过滤器材有限公司版权所有 Copyright ©  www.yl-guolv.com  Powered by 羽令集团—信息技术部