merck millipore,默克密理博,SF-1016,VE-Cadherin; Human, Cyanine 3 RNA Detection Probe,SmartFlare

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Merck Millipore 默克密理愽

Entrez Gene Number	Species Reactivity
NM_001795.3	H

描述
产品目录编号	SF-1016
商名	SmartFlare
描述	VE-Cadherin; Human, Cyanine 3 RNA Detection Probe \| SmartFlare
Alternate Names	CD144 CDH5 7B4
背景信息	With SmartFlare™ RNA Detection probes, you can detect RNA in LIVE CELLS with ease. With just an overnight incubation of VE-Cadherin; Human, Cyanine 3 RNA Detection Probe you can detect the presence of VE-Cadherin within your cells. VE-cadherin is an endothelial specific adhesion molecule that is essential for the maintenance of endothelial barrier function and angiogenesis. It is linked to the actin cytoskeleton through a number of adaptor proteins including alpha, beta, and gamma catenin. Cytoskeletal dynamics and phosphorylation regulate VE-cadherin mediated cell--cell adhesion. The interaction between cytosolic c-terminal Src kinase, SH2 domain and phosphorylated tyrosine 658 site of VE-Cadherin regulates density dependent cell proliferation. Phosphorylation of tyrosine 658 has been shown to lead to uncoupling of p120-catenin from the cytoplasmic tail of VE-cadherin. This phosphorylation event is sufficient to maintain cells in a mesenchymal state during the cell invasion phase of angiogenesis.

产品信息
格式	Cyanine 3
演示	Lyophilized

应用
应用	Use SmartFlare RNA Detection probes to measure gene expression in live cells. With an overnight incubation of SmartFlare VE-Cadherin, Human, Cyanine 3, you can detect VE-Cadherin RNA levels within your cells.
主要应用	RNA Detection

产品使用声明
质量保证	SmartFlare Probes have been tested in a buffer system to detect the release of the fluorophore in the presence of a complimentary base pair sequence for each lot to confirm target specificity. SmartFlare Probes have also been tested in a cell model system and demonstrated increased fluorescence in cells expressing the target compared to a negative SmartFlare Scramble Control.
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Store at 2–8°C in lyophilized format ONLY. Room temperature is required for reconstituted product.

包装信息
数量	250 reactions

merck millipore,默克密理博,SF-1016,VE-Cadherin; Human, Cyanine 3 RNA Detection Probe,SmartFlare

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