merck millipore,默克密理愽
  • merck millipore,默克密理博,SCR045,Pancreatic Islet Cell Characterization Kit

  • merck millipore,默克密理博,SCR045,Pancreatic Islet Cell Characterization Kit

    产品名称：Pancreatic Islet Cell Characterization Kit
    产品型号：SCR045
    The Pancreatic Islet Cell Characterization Kit provides a convenient set of validated antibodies that allows researchers to reliably identify mature pancreatic islets cells.

    merck millipore,默克密理博,SCR045,Pancreatic Islet Cell Characterization Kit

  • 产品介绍
  • merck millipore,默克密理博,SCR045,Pancreatic Islet Cell Characterization Kit

    重要规格表

    主要应用
    ICC
    描述
    产品目录编号 SCR045
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Pancreatic Islet Cell Characterization Kit
    概述 The Pancreatic Islet Cell Characterization Kit (SCR045) provides a convenient set of validated antibodies that allows researchers to reliably identify mature pancreatic islets cells. Along with antibodies generated against discrete hormones secreted by alpha, beta, delta and gamma cells of the pancreatic islets, the kit includes PDX-1 (pancreatic duodenal homeobox gene-1), a master regulator of islet cell development and GLUT-2, a glucose transporter present in beta-islet cells. The pancreas functions as both an exocrine and endocrine organ. Exocrine functions include the secretion of digestive enzymes (trypsinogen, chymotrypsinogen, pancreatic lipase, and amylase) from pancreatic acinar cells into the gastrointestinal tract. Endocrine functions occur within small clusters of heterogeneous cells, called the islets of Langerhans that are dispersed throughout the pancreatic tissue. The pancreatic islets comprise specific cell populations (alpha, beta, delta and gamma cells) that secrete distinct hormones:

    Alpha cells: Glucagon
    Beta cells: Insulin / proinsulin (c-peptide)
    Delta cells: Pancreatic polypeptide (PPP)
    Gamma cells: Somatostatin

    Diabetes results from the loss or dysfunction of insulin-producing beta-cells in the pancreas. Cell replacement therapies through islet transplantation is considered a potential long term approach to the control of blood glucose levels. However obtaining sufficient quantities of insulin-producing tissues for islet transplantation remains a major impediment. Stem cells (either from embryonic stem cells or from pancreatic progenitors) could potentially provide an abundant alternative source of islet cells for transplantation therapies.
    产品信息
    部件
    • 50 uL of Pancreatic Polypeptide (PPP) rabbit polyclonal (Part No: AB939-50UL)
    • 50 uL of Glucagon rabbit polyclonal (Part No: AB932-50UL)
    • 50 ug of Somatostatin rabbit polyclonal (Part No: AB5494-50UG)
    • 500 ug of Pro-insulin C-peptide mouse monoclonal (Part No: CBL94-500UG)
    • 100 uL of Glucose Transporter-2 (Glut-2) rabbit polyclonal (Part No: 07-1402)
    • 100 uL of PDX-1 rabbit polyclonal (Part No: AB3503)
    应用
    应用 The Pancreatic Islet Cell Characterization Kit provides a convenient set of validated antibodies that allows researchers to reliably identify mature pancreatic islets cells.
    主要应用
    • Immunocytochemistry
    应用说明 For further information on any of the included antibodies, please see the individual antibody datasheets:
    Rabbit anti-glucagon: Catalog No. AB932
    Rabbit anti-somatostatin: Catalog No. AB5494
    Mouse anti-pro-insulin C-peptide: Catalog No. CBL94
    Rabbit anti-glut-2: Catalog No. 07-1402
    Rabbit anti-PDX-1: Catalog No. AB3503
    Rabbit anti-PPP: Catalog No. AB939
    生物信息
    品种反应性 Mouse
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 All components are maintained at -20°C.
    包装信息
    数量 1 kit

    merck millipore,默克密理博,SCR045,Pancreatic Islet Cell Characterization Kit

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