merck millipore,默克密理愽
  • merck millipore,默克密理博,14-736M,TAO2 Protein, active, 250 µg

  • merck millipore,默克密理博,14-736M,TAO2 Protein, active, 250 µg

    产品名称：TAO2 Protein, active, 250 µg
    产品型号：14-736M
    Active, N-terminal 6His-tagged, recombinant, TAO2. TAO2 is a MAP3K that doubly phosphorylates & activates the MAP2Ks, MEK3 & MEK6. For use in Kinase Assays.

    merck millipore,默克密理博,14-736M,TAO2 Protein, active, 250 µg

  • 产品介绍
  • merck millipore,默克密理博,14-736M,TAO2 Protein, active, 250 µg

    描述
    产品目录编号 14-736M
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 TAO2 Protein, active, 250 µg
    概述 N-terminal 6His-tagged, recombinant, TAO2. TAO2 is a mitogen-activated protein kinase kinase kinase (MAP3K) that doubly phosphorylates and activates the MAP kinase kinases (MAP2Ks) MEK3 and MEK6.
    产品信息
    演示 10 μg of enzyme in 100 μL of 50 mM Tris/HCl pH7.5, 300 mM NaCl, 0.1 mM EGTA, 0.03% Brij 35, 270 mM sucrose, 1 mM benzamidine, 0.2 mM PMSF, 0.1% 2-mercaptoethanol. Frozen solution.
    应用
    应用 Active, N-terminal 6His-tagged, recombinant, TAO2. TAO2 is a MAP3K that doubly phosphorylates & activates the MAP2Ks, MEK3 & MEK6. For use in Kinase Assays.
    主要应用
    • Kinase Assay
    生物信息
    纯度 Purity 84% by SDS PAGE and Coomassie blue staining.
    来源 expressed in Sf21 cells
    品种 Human
    特异活性 1562 U/mg, where one unit of TOA2 activity is defined as 1 nmol phosphate incorporated into 0.8 mg/mL myelin basic per minute at 30°C with a final ATP concentration of 100 μM.
    Entrez基因编号
    • NM_016151.2
    • NM_004783.2
    基因符号
    • PSK-1
    • TAOK2
    • TAO1
    • TAO2
    • PSK
    • PSK1
    • MAP3K17
    • KIAA0881
    • hKFC-C
    蛋白靶 TAO2
    纯化方法 Ni2+/NTA-agarose
    靶子系列 STE
    UniProt编号
    • Q9UL54
    UniProt汇总 FUNCTION: SwissProt: Q9UL54 # Activates the JNK MAP kinase pathway through the specific activation of the upstream MKK3 and MKK6 kinases.
    COFACTOR: Magnesium (By similarity).
    SIZE: 1235 amino acids; 138251 Da
    SUBUNIT: Interacts with MKK3 and MKK6 (By similarity). Self- associates.
    SUBCELLULAR LOCATION: Cytoplasmic vesicle membrane; Multi-pass membrane protein (Potential). Note=Found to be perinuclear and localized to vesicular compartment.
    TISSUE SPECIFICITY: Ubiquitously expressed, with a higher level of expression in testis and brain.
    SIMILARITY: SwissProt: Q9UL54 ## Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily. & Contains 1 protein kinase domain.
    产品使用声明
    质量保证 Routinely evaluated by phosphorylation of 0.8 mg/ml myelin basic protein (MBP). Purity was assessed by SDS-PAGE and Coomassie blue staining using 3 μg of TAO2.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Stable for 6 months at -70°C from date of shipment. For maximum recovery of product, centrifuge original vial prior to removing the cap.
    Rapidly thaw the vial under cold water and immediately place on ice. Aliquot unused material into pre-chilled microcentrifuge tubes and immediately snap-freeze the vials in liquid nitrogen prior to re-storage at -70°C.
    包装信息
    数量 250 µg
    包装 Also available in 10 μg size (cat#14-736) and in bulk (cat# 14-736-K).

    merck millipore,默克密理博,14-736M,TAO2 Protein, active, 250 µg

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