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merck millipore,默克密理博,14-339M,Akt2/PKBβ (δPH, S474D) Protein, active, 250 µg
产品名称:Akt2/PKBβ (δPH, S474D) Protein, active, 250 µg
产品型号:14-339M
Active, recombinant human PKBβ, residues 120-481, S474D, containing an N-terminal His6 tag, activated by PDK1. For use in Kinase Assays.
merck millipore,默克密理博,14-339M,Akt2/PKBβ (δPH, S474D) Protein, active, 250 µg
- 产品介绍
描述 产品目录编号 14-339M 品牌系列 Upstate
商名 - Upstate
描述 Akt2/PKBβ (δPH, S474D) Protein, active, 250 µg 概述 Recombinant human PKBβ, residues 120-481, S474D, containing an N-terminal His6 tag; activated by PDK1. 应用 应用 Active, recombinant human PKBβ, residues 120-481, S474D, containing an N-terminal His6 tag, activated by PDK1. For use in Kinase Assays. 主要应用 - Kinase Assay
生物信息 来源 Expressed by baculovirus in Sf21 insect cells. 品种 Human 特异活性 For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme. Entrez基因编号 - NM_001626.3
Entrez基因汇总 This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. The gene was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phophorylating several known proteins. 基因符号 - RAC-PK-beta
- AKT2
- RAC-BETA
- PRKBB
- PKBBETA
蛋白靶 Akt2/PKBβ 纯化方法 Ni2+/NTA-agarose & heparin-Sepharose™ chromatography 靶子系列 AGC UniProt编号 - P31751
UniProt汇总 FUNCTION: SwissProt: P31751 # General protein kinase capable of phosphorylating several known proteins.
SIZE: 481 amino acids; 55769 Da
TISSUE SPECIFICITY: In all human cell types so far analyzed.
DISEASE:SwissProt: P31751 # Alterations of AKT2 may contribute to the pathogenesis of ovarian carcinomas.
SIMILARITY: SwissProt: P31751 ## Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. RAC subfamily. & Contains 1 AGC-kinase C-terminal domain. & Contains 1 PH domain. & Contains 1 protein kinase domain.产品使用声明 质量保证 Routinely evaluated by phosphorylation of Crosstide 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 1 year at -70°C 包装信息 数量 250 µg 包装 Also available in 10 μg size (cat#14-339) and in bulk (cat# 14-339-K).
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