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merck millipore,默克密理博,MABT107,Anti-Src-like-adapter Antibody/SLAP1, clone 1D9.1
产品名称：Anti-Src-like-adapter Antibody/SLAP1, clone 1D9.1
产品型号：MABT107
This Anti-Src-like-adapter Antibody/SLAP1, clone 1D9.1 is validated for use in western blotting for the detection of Src-like-adapter/SLAP1.
merck millipore,默克密理博,MABT107,Anti-Src-like-adapter Antibody/SLAP1, clone 1D9.1
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H WB M Purified Monoclonal Antibody 描述 产品目录编号 MABT107 描述 Anti-Src-like-adapter Antibody/SLAP1, clone 1D9.1 Alternate Names - hSLAP
- Src-like-adapter
- Src-like-adapter protein 1
- SLAP-1
背景信息 Src-like-adapter/SLAP1 protein, also known as SLAP, and encoded by the gene SLA/SLAP/SLAP1, is an adapter protein which negatively regulates T cell receptor signaling by inhibiting T cell antigen induced proliferation and works to control the positive selection and mitosis of T cells. SLAP1 also acts to connect signaling proteins such as ZAP70 with the T cell specific CBL ubiquitin ligase that plays a central role in degrading signaling proteins, and a critical role in limiting or initiating the T-cell specific- antigen-specific immunotolerance limits in T cells activation. Src-like-adapter/SLAP1 is localized to the cytoplasm and endosomes within cells. Src-like-adapter/SLAP1 is expressed in lung and fetal brain, and weakly expressed in heart, adult brain, placenta, liver, skeletal muscle, kidney and pancreas. Recent research suggest that SLAP1 may also play a role in different cancers and in modulation of receptor tyrosine kinase signaling in cancers apart from its conventional role in regulation of T cell receptor stability. 产品信息 格式 Purified 演示 Purified mouse monoclonal IgMκ in buffer containing PBS with 0.05% sodium azide. 应用 应用 This Anti-Src-like-adapter Antibody/SLAP1, clone 1D9.1 is validated for use in western blotting for the detection of Src-like-adapter/SLAP1. 主要应用 - Western Blotting
生物信息 免疫原品种 Linear peptide corresponding to human Src-like-adapter/SLAP1. 克隆 1D9.1 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Mouse 同种型 IgMκ 品种反应性 Human 抗体类型 Monoclonal Antibody Entrez基因编号 - NP_006739
基因符号 - SLAP1
- SLA
- SLAP
纯化方法 Purified by ion-exchange chromatography UniProt编号 - Q13239
产品使用声明 质量保证 Evaluated by Western Blotting in Human Lung tissue lysate.
Western Blotting Analysis: A 1:5,000 dilution of this antibody detected Src-like-adapter/SLAP1 in 400 µg of human lung tissue lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µL
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