- 当前位置：首页 > >Merck Millipore > 生命科学研究
- 生命科学研究
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 M, H, R WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 09-466 品牌系列 Upstate
商名 - Upstate
描述 Anti-phospho-CrkL (Tyr207) Antibody 背景信息 CRKL belongs to a family of adaptor proteins containing SH2/SH3 domains that couple to effector proteins including p130CAS, SOS, Abl, and Arg. CRKL plays a role in the mediation of Integrin- and Rac-dependent cell migration and in Ras-dependent activation of JNK. The protein is also involved in T-cell activation. Phosphorylation of CrkL on Tyr207 is known to be correlated with its inhibition. 产品信息 格式 Affinity Purified 控制 - K562
演示 Purified rabbit polyclonal IgG in storage buffer containing PBS with 0.05% sodium azide in 50% glycerol. 应用 应用 Detect phospho-CrkL (Tyr207) using this Anti-phospho-CrkL (Tyr207) Antibody validated for use in WB. 主要应用 - Western Blotting
生物信息 免疫原品种 KLH synthetic peptide including and encompassing Tyr 207 of human CrkL. 宿主 Rabbit 特异性 Recognizes CrkL only when phosphorylated on Tyr207. 品种反应性 MouseHumanRat 抗体类型 Polyclonal Antibody Entrez基因编号 - NP_005198
Entrez基因汇总 NP_005198.1 基因符号 - Crk Like
- v-crk avian sarcoma virus CT10 oncogene homolog-like
- v-crk sarcoma virus CT10 oncogene homolog (avian)-like
修改 - Phosphorylation
UniProt编号 - P46109
UniProt汇总 FUNCTION: May mediate the transduction of intracellular signals.
SIZE: 303 amino acids; 33777 Da
SUBUNIT STRUCTURE:Interacts with INPP5D/SHIP1. Interacts with DOCK2 and EPOR. Interacts with phosphorylated CBLB and IRS4.
SIMILARITY: Contains 1 SH2 domain.Contains 2 SH3 domains.产品使用声明 质量保证 Routinely evaluated by western blot on K563 cell lysates. 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt.
Handling Recommendations: Upon receipt, and prior to removing the cap, centrifuge the vial and gently mix the solution. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
包装信息 数量 100 µL
上一件merck millipore产品：merck millipore,默克密理博,MAB5450,Anti-Tau Antibody, phosphoThreonine 231, clone PHF-6
下一件merck millipore产品：merck millipore,默克密理博,04-1570-I,Anti-RNA polymerase II subunit B1 (phospho-CTD Ser-7) Antibody, clone 4E12
相关产品
merck millipore,默克密理博,ABE181,Anti-LBP-1a Antibody
merck millipore,默克密理博,MABT107,Anti-Src-like-adapter Antibody/SLAP1, clone 1D9.1
merck millipore,默克密理博,IL011,Interleukin-11, recombinant
merck millipore,默克密理博,AB21-K,Goat Anti-Rabbit IgG
merck millipore,默克密理博,MAB5450,Anti-Tau Antibody, phosphoThreonine 231, clone PHF-6
merck millipore,默克密理博,SF-451,miR-181a-5p; Human, Cyanine 5, RNA Detection Probe,SmartFlare
merck millipore,默克密理博,MABC685,Anti-ENC1 Antibody, clone EPR5406(B), rabbit monoclonal
merck millipore,默克密理博,06-667,Anti-JAK3 Antibody, CT
merck millipore,默克密理博,SF-1214,PARK2; Ms, Cyanine 3 RNA Detection Probe,SmartFlare