merck millipore,默克密理博,MABS749,Anti-Calmodulin, clone EPR5028, Rabbit Monoclonal Antibody

搜索"Merck Millipore 密理愽"产品

Merck Millipore 默克密理愽

当前位置：首页 > >Merck Millipore > 生命科学研究
生命科学研究

merck millipore,默克密理博,MABS749,Anti-Calmodulin, clone EPR5028, Rabbit Monoclonal Antibody
产品名称：Anti-Calmodulin, clone EPR5028, Rabbit Monoclonal Antibody
产品型号：MABS749
This Anti-Calmodulin, clone EPR5028, Rabbit Monoclonal Antibody is validated for use in Western Blotting and Flow Cytometry for the detection of Calmodulin.

merck millipore,默克密理博,MABS749,Anti-Calmodulin, clone EPR5028, Rabbit Monoclonal Antibody

产品介绍

merck millipore,默克密理博,MABS749,Anti-Calmodulin, clone EPR5028, Rabbit Monoclonal Antibody

重要规格表

品种反应性	主要应用	宿主	格式	抗体类型
M, H	FC, WB	Rb	Unpurified	Monoclonal Antibody

描述
产品目录编号	MABS749
描述	Anti-Calmodulin, clone EPR5028, Rabbit Monoclonal Antibody
Alternate Names	CaM Calmodulin
背景信息	Calmodulin (CaM) is a ubiquitous, calcium-binding protein that can bind to and regulate a multitude of different protein targets, thereby affecting many different cellular functions. Calmodulin mediates processes such as inflammation, metabolism, apoptosis, muscle contraction, intracellular movement, short-term and long-term memory, nerve growth and the immune response. Calmodulin is expressed in many cell types and can have different subcellular locations, including the cytoplasm, within organelles, or associated with the plasma or organelle membranes. Many of the proteins that Calmodulin binds are unable to bind calcium themselves, and as such use Calmodulin as a calcium sensor and signal transducer. Calmodulin undergoes a conformational change upon binding to calcium, which enables it to bind to specific proteins for a specific response. Calmodulin can bind up to four calcium ions, and can undergo post-translational modifications, such as phosphorylation, acetylation, methylation and proteolytic cleavage, each of which can potentially modulate its actions.

产品信息
格式	Unpurified
演示	Rabbit monoclonal in buffer containing PBS with up to 0.1% sodium azide, 0.05% BSA, and 50% glycerol.

应用
应用	This Anti-Calmodulin, clone EPR5028, Rabbit Monoclonal Antibody is validated for use in Western Blotting and Flow Cytometry for the detection of Calmodulin.
主要应用	Flow Cytometry Western Blotting
应用说明	Flow Cytometry Analysis: A 1:100-1,000 dilution from a representative lot detected Calmodulin in SH-SY5Y cells. Produced in collaboration with Epitomics™

生物信息
免疫原品种	Synthetic peptide corresponding to the N-terminus of human Calmodulin.
表位	N-terminus
克隆	EPR5028
浓缩	Please refer to lot specific datasheet.
宿主	Rabbit
同种型	IgG
品种反应性	MouseHuman
Species Reactivity Note	Human, Mouse
抗体类型	Monoclonal Antibody
基因符号	CAMIII CALM1 CALM CAM CAM1 ;CALM2 CAM2 CAMB ;CALM3 CALML2 CAM3 CAMC
纯化方法	Unpurified
UniProt编号	P62158

产品使用声明
质量保证	Evaluated by Western Blotting in HeLa, Ramos, HCT116 and NIH/3T3 cell lysates. Western Blotting Analysis: A 1:50,000-200,000 dilution of this antibody detected Calmodulin in HeLa, Ramos, HCT116 and NIH/3T3 cell lysates.
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.

储存和货运信息

存储条件

Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.