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品种反应性 主要应用 宿主 格式 抗体类型 H FC, WB M Purified Monoclonal Antibody 描述 产品目录编号 MABS460 描述 Anti-FGF23 Antibody, clone 278-2 Alternate Names - Fibroblast growth factor 23 C-terminal peptide
- Fibroblast growth factor 23
- FGF-23
- Phosphatonin
- Tumor-derived hypophosphatemia-inducing factor
- Fibroblast growth factor 23 N-terminal peptide
背景信息 Fibroblast growth factor 23 (FGF-23) is also called Phosphatonin and Tumor-derived hypophosphatemia-inducing factor. FGF-23 belongs to the heparin-binding growth factors family and has several important functions including: regulation of phosphate homeostasis, inhibition of renal tubular phosphate transport, upregulation of EGR1 expression, regulation of vitamin-D metabolism, and negative regulation of osteoblast differentiation and matrix mineralization. FGF-23 is expressed in osteogenic cells, adult trabecular bone, osteocytes and flattened bone-lining cells (inactive osteoblasts). Defects in FGF23 can lead to autosomal dominant hypophosphataemic rickets (ADHR) and hyperphosphatemic familial tumoral calcinosis (HFTC). 产品信息 格式 Purified 控制 - Human salivary gland tissue lysate
演示 Purified mouse monoclonal IgG1κ in buffer containing PBS with 0.05% sodium azide. 应用 应用 Anti-FGF23 Antibody, clone 278-2 is a mouse monoclonal antibody & validated for use in western blotting. 主要应用 - Flow Cytometry
- Western Blotting
应用说明 Flow Cytometry Analysis: 2 µg from a representative lot detected FGF23 in Jurkat and human PMBC cells. 生物信息 免疫原品种 Corresponding to human FGF23. 克隆 278-2 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Mouse 同种型 IgG1κ 品种反应性 Human 抗体类型 Monoclonal Antibody Entrez基因编号 - NP_065689
基因符号 - HYPF
- FGF23
纯化方法 Protein A purified UniProt编号 - Q9GZV9
产品使用声明 质量保证 Evaluated by Western Blotting in human salivary gland tissue lysate.
Western Blotting Analysis: 0.5 µg/mL of this antibody detected FGF23 in 10 µg of human salivary gland tissue lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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