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品种反应性 主要应用 宿主 格式 抗体类型 Eq, M, H IHC, WB R Purified Monoclonal Antibody 描述 产品目录编号 MABS330 描述 Anti-SFRP2 Antibody, clone 8H1 Alternate Names - SARP-1
- Secreted frizzled-related protein 2
- FRP-2
- sFRP-2
- Secreted apoptosis-related protein 1
背景信息 Secreted frizzled-related proteins (SFRPs) may play a critical role in carcinogenesis by inhibiting the Wnt/beta-catenin signaling pathway. Secreted frizzled-related protein 2 (SFRP2) may be useful to further investigate mammary tumorigenesis as its expression increases with tumor progression in canine mammary gland tumors. SFRP2 in mouse embryos has been found to cause severe shortening of the thoracic region. Studies have shown that this protein is the essential stem cell paracrine factor that is thought to regulate myocardial survival and repair damage in the aftermath of an ischemic injury. 产品信息 格式 Purified 控制 - Mouse eye tissue lysate
演示 Purified rat monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 Detect SFRP using this rat monoclonal antibody, Anti-SFRP2 Antibody, clone 8H1 validated for use in western blotting & IHC. 主要应用 - Immunohistochemistry
- Western Blotting
应用说明 Western Blotting Analysis: A representative lot from an independent laboratory detected SFRP2 in RMG cell lysate and in ERU retinal tissue lysate (Hauck, S. M., et al. (2012). Journal of Proteomics. 75:4545-4554).
Immunohistochemistry Analysis: A representative lot from an independent laboratory detected SFRP2 in equine retinal tissue (Hauck, S. M., et al. (2012). Journal of Proteomics. 75:4545-4554).生物信息 免疫原品种 Recombinant protein corresponding to human SFRP2. 克隆 8H1 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rat 同种型 IgG2aκ 品种反应性 HorseMouseHuman Species Reactivity Note Demonstrated to react with Mouse. Predicted to react with human based upon immunogen design. Predicted to react with Equine based on 100% sequence homology. 抗体类型 Monoclonal Antibody Entrez基因编号 - NP_003004
基因符号 - UNQ361/PRO697
- SFRP2
- FRP2
- SARP1
- FKSG12
纯化方法 Protein G purified UniProt编号 - Q96HF1
产品使用声明 质量保证 Evaluated by Western Blotting in mouse eye tissue lysate.
Western Blotting Analysis: 2.0 µg/mL of this antibody detected SFRP2 in 10 µg of mouse eye tissue lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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