merck millipore,默克密理愽
  • merck millipore,默克密理博,AB15522,Anti-Neuronal pentraxin 1 Receptor Antibody

  • merck millipore,默克密理博,AB15522,Anti-Neuronal pentraxin 1 Receptor Antibody

    产品名称：Anti-Neuronal pentraxin 1 Receptor Antibody
    产品型号：AB15522
    This Anti-Neuronal pentraxin 1 Receptor Antibody is validated for use in ELISA, WB for the detection of Neuronal pentraxin 1 Receptor.

    merck millipore,默克密理博,AB15522,Anti-Neuronal pentraxin 1 Receptor Antibody

  • 产品介绍
  • merck millipore,默克密理博,AB15522,Anti-Neuronal pentraxin 1 Receptor Antibody

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    MWB, ELISARbPurifiedPolyclonal Antibody
    描述
    产品目录编号 AB15522
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Anti-Neuronal pentraxin 1 Receptor Antibody
    Alternate Names
    • NPXR1
    背景信息 Neuronal Pentraxins: A new family of putative integral membrane pentraxins or Neuronal pentraxins identified through interaction with a presynaptic snake venom toxin taipoxin. NPX1, NPX2 and NPXR (Neuronal Pentraxin Receptor), the three neuronal pentraxins represent a novel neuronal uptake pathway that may function during synapse formation and remodeling. The N-terminal half of neuronal pentraxins are 20-30% identical to previously identified pentraxins (CRP and SAP), the three neuronal pentraxins are 50% identical to each other and are significantly larger than the classical pentraxins (>50 versus 30kDa), suggesting that they may have additional novel functions. NPXR1 (Neuronal Pentraxin Receptor 1) a 493aa protein in mouse, 494 in rat, and 499aa in human. The predominant form of NPXR contains a putative NH2 terminal transmembrane and all forms are glycosylated. It shows 49 and 48% homology with NPX1 and NPX2 respectively. NPXR message is expressed in neuronal regions that express NPX1 and NPX2.
    产品信息
    格式 Purified
    演示 Liquid in PBS with 0.1% BSA.
    应用
    应用 This Anti-Neuronal pentraxin 1 Receptor Antibody is validated for use in ELISA, WB for the detection of Neuronal pentraxin 1 Receptor.
    主要应用
    • Western Blotting
    • ELISA
    应用说明 Western blot: 1-10 µg/mL using ECL.
    Immunohistochemistry: Not tested. It is recommended that the antibody be tried at 2-20 µg/mL
    ELISA: 0.5-1 µg/mL using control peptide.
    Optimal working dilutions must be determined by end user.
    生物信息
    免疫原品种 Synthetic peptide near the C-terminus of mouse NPXR1
    宿主 Rabbit
    特异性 Neuronal pentraxin 1 Receptor (NPXR1).
    品种反应性 Mouse
    Species Reactivity Note Other species have not yet been tested. The immunogen sequence is 100% conserved in rat, and human NPXR1.
    抗体类型 Polyclonal Antibody
    Entrez基因编号
    • NM_014293.2
    Entrez基因汇总 This gene encodes a protein similar to the rat neuronal pentraxin receptor. The rat pentraxin receptor is an integral membrane protein that is thought to mediate neuronal uptake of the snake venom toxin, taipoxin, and its transport into the synapses. Studies in rat indicate that translation of this mRNA initiates at a non-AUG (CUG) codon. This may also be true for mouse and human, based on strong sequence conservation amongst these species.
    基因符号
    • NPR
    • NPTXR
    纯化方法 Immunoaffinity purified
    UniProt编号
    • O95502
    UniProt汇总 COFACTOR: Binds 2 calcium ions per subunit (By similarity).
    SIZE: 499 amino acids; 52718 Da
    SUBCELLULAR LOCATION: Membrane; Single-pass type II membrane protein (Potential).
    SIMILARITY: SwissProt: O95502 ## Contains 1 pentaxin domain.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.
    包装信息
    数量 50 µg

    merck millipore,默克密理博,AB15522,Anti-Neuronal pentraxin 1 Receptor Antibody

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