merck millipore,默克密理博,MABS184,Anti-FABP7 Antibody, clone EPR4000, Rabbit,MABS184

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merck millipore,默克密理博,MABS184,Anti-FABP7 Antibody, clone EPR4000, Rabbit,MABS184
产品名称：Anti-FABP7 Antibody, clone EPR4000, Rabbit, MABS184
产品型号：MABS184

merck millipore,默克密理博,MABS184,Anti-FABP7 Antibody, clone EPR4000, Rabbit,MABS184

产品介绍

merck millipore,默克密理博,MABS184,Anti-FABP7 Antibody, clone EPR4000, Rabbit,MABS184

重要规格表

品种反应性	主要应用	宿主	格式	抗体类型
H	ICC, WB	Rb	Diluted Culture Supernatant	Monoclonal Antibody

描述
产品目录编号	MABS184
描述	Anti-FABP7 Antibody, clone EPR4000, Rabbit \| MABS184
Alternate Names	mammary-derived growth inhibitor-related fatty acid-binding protein, brain brain lipid binding protein Mammary-derived growth inhibitor related Fatty acid-binding protein 7 Brain-type fatty acid-binding protein Brain lipid-binding protIEN fatty acid binding protein 7, brain
背景信息	FABP7 is a member of the large family of hydrophobic ligand-binding proteins (FABPs) (1). FABP proteins are involved in lipid metabolism, including uptake and intracellular trafficking of fatty acids and retinoids. In addition, they play a role in gene regulation, cell signaling, cell growth and differentiation. Several reports have suggested a possible role for the different FABP proteins in cancer biology, linking their levels with either increasing or decreasing the degree of malignancy. Nine FABPs (FABP1-FABP9) have been identified (2). FABP7 is a brain-specific protein that is required for the establishment of the radial glial fiber system in the developing brain, a system that is necessary for the migration of immature neurons to establish cortical layers (3). It is expressed at high levels in the developing central nervous system (4). FABP7 has also been found in melanocytic lesions and has shown to regulate proliferation and invasion in melanoma cells in vitro, suggesting that it may play a role in cell proliferation and invasion (2).

产品信息
格式	Diluted Culture Supernatant
控制	Fetal brain tissue lysate
演示	Rabbit Monoclonal in buffer containing 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl containing 40% Glycerol, 0.01% sodium azide and 0.05% BSA.

应用
主要应用	Immunocytochemistry Western Blotting
应用说明	Immunocytochemistry Analysis: 1:10-1:100 dilution from a representative lot was used in IC.

生物信息
免疫原品种	Synthetic peptide corresponding to human FABP7.
克隆	EPR4000
宿主	Rabbit
同种型	IgG
品种反应性	Human
Species Reactivity Note	Demonstrated to react with Human.
抗体类型	Monoclonal Antibody
Entrez基因编号	O15540
基因符号	DKFZp547J2313 BLBP B-FABP FABPB MRG
纯化方法	Unpurified
UniProt编号	O15540
UniProt汇总	FUNCTION: B-FABP could be involved in the transport of a so far unknown hydrophobic ligand with potential morphogenic activity during CNS development. It is required for the establishment of the radial glial fiber system in developing brain, a system that is necessary for the migration of immature neurons to establish cortical layers By similarity. SUBCELLULAR LOCATION: Cytoplasm. TISSUE SPECIFICITY: Expressed in brain and other neural tissues. DOMAIN: Forms a beta-barrel structure that accommodates the hydrophobic ligand in its interior. SEQUENCE SIMILARITIES: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

产品使用声明
质量保证	Evaluated by Western Blot in fetal brain tissue lysate. Western Blot Analysis: A 1:1,000-1:10,000 dilution of this antibody detected FABP7 in fetal brain tissue lysate.
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Stable for 1 year at -20ºC from date of receipt. Handling Recommendations: Upon first thaw, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.

储存和货运信息

存储条件

Stable for 1 year at -20ºC from date of receipt. Handling Recommendations: Upon first thaw, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.