merck millipore,默克密理愽
  • merck millipore,默克密理博,565755,γ-Secretase Inhibitor II - Calbiochem

  • merck millipore,默克密理博,565755,γ-Secretase Inhibitor II - Calbiochem

    产品名称：γ-Secretase Inhibitor II - Calbiochem
    产品型号：565755
    The γ-Secretase Inhibitor II controls the biological activity of γ-Secretase. This small molecule/inhibitor is primarily used for Neuroscience applications.

    merck millipore,默克密理博,565755,γ-Secretase Inhibitor II - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,565755,γ-Secretase Inhibitor II - Calbiochem

    重要规格表

    经验配方
    C₃₃H₅₇F₂N₅O₉
    描述
    概述 A cell-permeable, reversible and selective peptidomimetic inhibitor of γ-secretase (IC50 = 13 µM for Aβ). Displays only weak inhibitory activity against calpain II (IC50 = 100 µM in a purified enzyme assay).

    Please note that the molecular weight for this compound is batch-specific due to variable water content.
    产品目录编号 565755
    品牌系列 Calbiochem®
    同义词 MW167
    参考
    参考 Wolfe, M.S., et al. 1999. Biochemistry 38, 4720.
    Wolfe, M.S., et al. 1998. J. Med. Chem. 41, 6.
    Citron, M., et al. 1996. Proc. Natl. Acad. Sci. USA 93, 13170.
    产品信息
    具有ATP竞争性 N
    形式 White solid
    Hill配方 C₃₃H₅₇F₂N₅O₉
    化学配方 C₃₃H₅₇F₂N₅O₉
    可逆 Y
    结构配方图像
    生物信息
    主靶 γ-secretase
    主靶IC50 13 µM against γ-secretase
    纯度 ≥95% by HPLC
    理化信息
    细胞可渗透 Y
    溶解度 DMSO
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 -20°C
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

    merck millipore,默克密理博,565755,γ-Secretase Inhibitor II - Calbiochem

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