• merck millipore,默克密理博,MABN98,Anti-SATB2 Antibody, clone 2B12.2
  • merck millipore,默克密理博,MABN98,Anti-SATB2 Antibody, clone 2B12.2

    产品名称:Anti-SATB2 Antibody, clone 2B12.2
    产品型号:MABN98
    Detect SATB2 using this mouse monoclonal antibody, Anti-SATB2 Antibody & clone 2B12.2 validated for use in western blotting.

    merck millipore,默克密理博,MABN98,Anti-SATB2 Antibody, clone 2B12.2

  • 产品介绍
  • merck millipore,默克密理博,MABN98,Anti-SATB2 Antibody, clone 2B12.2

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    R, H, MWBMPurifiedMonoclonal Antibody
    描述
    产品目录编号 MABN98
    描述 Anti-SATB2 Antibody, clone 2B12.2
    Alternate Names
    • Special AT-rich sequence-binding protein 2
    • DNA-binding protein SATB2
    背景信息 DNA-binding protein SATB2 (SATB2) is also known as Special AT-rich sequence-binding protein 2. SATB2 binds to DNA at nuclear matrix- or scaffold-associated regions. SATB2 is critical for the initiation of the upper-layer neurons (UL1) specific genetic program and the inactivation of deep-layer neurons (DL) and UL2 specific genes, represses Ctip2 and regulates corticocortical connections in the developing cerebral cortex. SATB2 acts as a transcription factor controlling nuclear gene expression by inducing chromatin-loop remodeling. SATB2 is also a docking site for, and recruits chromatin remodeling enzymes, corepressors (HDACs) and coactivators (HATs) directly to promoters and enhancers. SATB2 is highly expressed in adult brain, with moderate to weak expression in fetal brain, adult liver, kidney, spinal cord, amygdala, corpus callosum, caudate nucleus, and hippocampus. Defects and chromosomal aberrations involving SATB2 are found in isolated cleft palate and Toriello-Carey syndrome.
    产品信息
    格式 Purified
    控制
    • Human colon tissue lysate.
    演示 Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
    应用
    应用 Detect SATB2 using this mouse monoclonal antibody, Anti-SATB2 Antibody & clone 2B12.2 validated for use in western blotting.
    主要应用
    • Western Blotting
    应用说明 Western Blotting Analysis: 1 µg/mL from a representative lot detected SATB2 in 10 µg of Raji cell lysate.

    Western Blotting Analysis: 0.5 µg/mL from a representative lot detected SATB2 in 10 µg mouse, rat, and human cell lysate.
    生物信息
    免疫原品种 Recombinant protein corresponding to human SATB2.
    克隆 2B12.2
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Mouse
    同种型 IgG1κ
    品种反应性 RatHumanMouse
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • NP_001165980
    基因符号
    • SATB2
    纯化方法 Protein G purified
    UniProt编号
    • Q9UPW6
    产品使用声明
    质量保证 Evaluated by Western Blotting in human colon tissue lysate.

    Western Blotting Analysis: 0.25 µg/mL of this antibody detected SATB2 in 10 µg of human colon tissue lysate.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Stable for 1 year at 2-8°C from date of receipt.
    包装信息
    数量 100 µg

    merck millipore,默克密理博,MABN98,Anti-SATB2 Antibody, clone 2B12.2

上一件merck millipore产品:merck millipore,默克密理博,MABE954,Anti-phospho RNA Pol II (Ser5), clone 1H4B6 Antibody
下一件merck millipore产品:merck millipore,默克密理博,HTS146M,ChemiSCREEN™ Membrane Preparation Recombinant Human mGLU2 Metabotropic Glutamate Receptor



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