merck millipore,默克密理博,203732,Brevetoxin PbTx-2, Ptychodiscus brevis - CAS 79580-28-2

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merck millipore,默克密理博,203732,Brevetoxin PbTx-2, Ptychodiscus brevis - CAS 79580-28-2 - Calbiochem
产品名称：Brevetoxin PbTx-2, Ptychodiscus brevis - CAS 79580-28-2 - Calbiochem
产品型号：203732
Lipid-soluble polyether neurotoxin that binds to Na+ channels on nerves and muscles causing an excessive influx of Na+ across membranes.

merck millipore,默克密理博,203732,Brevetoxin PbTx-2, Ptychodiscus brevis - CAS 79580-28-2 - Calbiochem

产品介绍

merck millipore,默克密理博,203732,Brevetoxin PbTx-2, Ptychodiscus brevis - CAS 79580-28-2 - Calbiochem

重要规格表

经验配方	CAS号
C₅₀H₇₀O₁₄	79580-28-2

描述
概述	Lipid-soluble polyether neurotoxin that binds to Na⁺ channels on nerves and muscles causing an excessive influx of Na⁺ across membranes. Binds at site 5 on the voltage-sensitive Na⁺ channel.
产品目录编号	203732
品牌系列	Calbiochem®
同义词	Brevetoxin B, GbTx-2

参考
参考	Edwards, R.A., et al. 1992. Mol. Brain Res. 14, 64. Trainer, V.L. 1991. Mol. Pharmacol. 40, 988. Tsai, M.C., and Chen, M.L. 1991. Br. J. Pharmacol. 103, 1126. Trainer, V.L., et al. 1990. ACS Symposium Series 418, 166. Baden, G. 1989. FASEB J. 3, 1807. Baden, D.G., et al. 1988. Toxicon 26, 97. Poli, M.A., et al. 1986. Mol. Pharmacol. 30, 129. Shimizu, Y., et al. 1986. J. Am. Chem. Soc. 108, 514. Nakanishi, K. 1985. Toxicon 23, 473. Baden, D.G., et al. 1982. Toxicon 19, 455. Catterfall, W.A., and Risk, M. 1981. Mol. Pharmacol. 19, 345.

参考

Edwards, R.A., et al. 1992. Mol. Brain Res. 14, 64.
Trainer, V.L. 1991. Mol. Pharmacol. 40, 988.
Tsai, M.C., and Chen, M.L. 1991. Br. J. Pharmacol. 103, 1126.
Trainer, V.L., et al. 1990. ACS Symposium Series 418, 166.
Baden, G. 1989. FASEB J. 3, 1807.
Baden, D.G., et al. 1988. Toxicon 26, 97.
Poli, M.A., et al. 1986. Mol. Pharmacol. 30, 129.
Shimizu, Y., et al. 1986. J. Am. Chem. Soc. 108, 514.
Nakanishi, K. 1985. Toxicon 23, 473.
Baden, D.G., et al. 1982. Toxicon 19, 455.
Catterfall, W.A., and Risk, M. 1981. Mol. Pharmacol. 19, 345.

产品信息
CAS号	79580-28-2
具有ATP竞争性	N
形式	Tan to white solid
Hill配方	C₅₀H₇₀O₁₄
化学配方	C₅₀H₇₀O₁₄
Molar Mass	895.1
可逆	N
结构配方图像

生物信息
主靶	Neurotoxin that binds to Na+ channels on nerves and muscles.
纯度	≥95% by HPLC

理化信息
细胞可渗透	N
溶解度	EtOH, MeOH or H₂O

GHS安全信息
RTECS	XW5886000

安全信息
R相	R: 26/27/28 Very toxic by inhalation, in contact with skin and if swallowed.
S相	S: 22-36/37/39-45 Do not breathe dust. Wear suitable protective clothing, gloves and eye/face protection. In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).

储存和货运信息
货运代码	Blue Ice Only
毒性	Highly Toxic
有害材料注意事项：	Due to the nature of the Hazardous Materials in this shipment, additional shipping chargesmay be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
储存	-20°C
无需冷冻	No
特殊指南	Following reconstitution, aliquot, purge with iniert gas and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C. From Catalog: Solubitlity- removed acetone, EtOAc
最终使用证书	Y