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merck millipore,默克密理博,MABN77,Anti-Potassium Channel Kv1.2 Antibody, clone K14/16
产品名称：Anti-Potassium Channel Kv1.2 Antibody, clone K14/16
产品型号：MABN77
This Anti-Potassium Channel Kv1.2 Antibody, clone K14/16 is validated for use in IH, WB, IF for the detection of Potassium Channel Kv1.2.
merck millipore,默克密理博,MABN77,Anti-Potassium Channel Kv1.2 Antibody, clone K14/16
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 R WB, IHC M Purified Monoclonal Antibody 描述 产品目录编号 MABN77 描述 Anti-Potassium Channel Kv1.2 Antibody, clone K14/16 Alternate Names - voltage-gated potassium channel protein Kv1.2
- potassium voltage-gated channel, shaker-related subfamily, member 2
- potassium voltage-gated channel subfamily A member 2
- Voltage-gated potassium channel subunit Kv1.2
- Voltage-gated potassium channel HBK5
- potassium channel
- Voltage-gated K(+) channel HuKIV
背景信息 Potassium channel Kv1.2 is one of many different types of potassium channels in the cell. The Kv family of potassium channels seem to have a conserved homotetramer formation consisting of four voltage sensors and one pore domain. Kv1.2 cooperates with cortactin (an actin cytoskeleton-binding protein) and together they may have a part in the regulation of the ionic current. 产品信息 格式 Purified 控制 - Rat brain membrane tissue lysate
演示 Purified mouse monoclonal IgG2bκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 This Anti-Potassium Channel Kv1.2 Antibody, clone K14/16 is validated for use in IH, WB, IF for the detection of Potassium Channel Kv1.2. 主要应用 - Western Blotting
- Immunohistochemistry
应用说明 Immunofluorescence Analysis: a previous lot of this antibody was used by an independent laboratory in IF. (Yang, J.W., et al. (2007). PNAS. 104(50):20055–20060.) 生物信息 免疫原品种 Recombinant protein corresponding to rat Kv1.2. 克隆 K14/16 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Mouse 同种型 IgG2bκ 品种反应性 Rat Species Reactivity Note Demonstrated to react with rat. 抗体类型 Monoclonal Antibody Entrez基因编号 - NP_037102
Entrez基因汇总 Delayed-rectifier K+ channel expressed in heart and brain [RGD]. 基因符号 - Kv1.2
- KCNA2
- HBK5
- RBK2
- HK4
- MK2
- KV1.2
- NGK1
- HUKIV
纯化方法 Protein G UniProt编号 - P63142
UniProt汇总 FUNCTION: Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient.
SUBUNIT STRUCTURE: Heterotetramer of potassium channel proteins. Binds PDZ domains of DLG1, DLG2 and DLG4.
SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
DOMAIN: The N-terminus may be important in determining the rate of inactivation of the channel while the tail may play a role in modulation of channel activity and/or targeting of the channel to specific subcellular compartments.
The segment S4 is probably the voltage-sensor and is characterized by a series of positively charged amino acids at every third position.
SEQUENCE SIMILARITIES: Belongs to the potassium channel family. A (Shaker) (TC 1.A.1.2) subfamily. Kv1.2/KCNA2 sub-subfamily. [View classification]产品使用声明 质量保证 Evaluated by Western Blot in rat brain membrane tissue lysate.
Western Blot Analysis: 0.5 µg/mL of this antibody detected Kv1.2 on 10 µg of rat brain membrane tissue lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
上一件merck millipore产品：merck millipore,默克密理博,14-661,ARK5 Protein, active, 10 µg
下一件merck millipore产品：merck millipore,默克密理博,MABT213,Anti-SHP-1 Antibody, clone HG213, rabbit monoclonal
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