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merck millipore,默克密理博,MABN690,Anti-PPP1CA Antibody, clone 5E9
产品名称：Anti-PPP1CA Antibody, clone 5E9
产品型号：MABN690
Anti-PPP1CA Antibody, clone 5E9 is a highly specific mouse monoclonal antibody & that targets Serine/threonine-protein phosphatase & has been tested in western blotting.
merck millipore,默克密理博,MABN690,Anti-PPP1CA Antibody, clone 5E9
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H WB M Ascites Monoclonal Antibody 描述 产品目录编号 MABN690 描述 Anti-PPP1CA Antibody, clone 5E9 Alternate Names - Serine/threonine-protein phosphatase PP1-alpha catalytic subunit
背景信息 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit (PP-1A) encoded by the gene named PPP1CA or PPP1A is one of the three catalytic subunits of protein phosphatase 1 (PP1), one of the major protein phosphatases in the cell. PPP1CA interacts with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate a huge variety of target proteins. PPP1CA is critical for cell division, chromatin structure, protein synthesis, glycogen metabolism, muscle and cardiac function as well as the regulation of long-term ionic conductances and even synaptic plasticity. Developmentally it has nearly as many roles with principal ones being as a regulator of neural tube and optic fissure closure as well as enteric neural crest cell (ENCCs) migration during development. PPP1CA can be found both cytoplasmically and nuclear localized depending upon its regulatory partner but PPP1CA is mostly nuclear/nucleoplasm localized. Interestingly in the brain, PPP1CA also functions as a suppressor of learning and memory and as a potential mediator of cognitive decline during aging. EMD-Millipore’s Anti-PPP1CA mouse monoclonal antibody has been tested in western blot on recombinant protein as well as cell lysates from HeLa, HepG2, MCF-7, Jurkat and A549 cells and by direct ELISA against varying concentrations of antigen. 产品信息 格式 Ascites 控制 - HeLa, HepG2, MCF-7, Jurkat, and A549 cell lysates
演示 Mouse monoclonal IgG1 ascitic fluid containing up to 0.1% sodium azide. 应用 应用 Anti-PPP1CA Antibody, clone 5E9 is a highly specific mouse monoclonal antibody & that targets Serine/threonine-protein phosphatase & has been tested in western blotting. 主要应用 - Western Blotting
生物信息 免疫原品种 Purified recombinant fragment of human PPP1CA expressed in E. Coli. 克隆 5E9 宿主 Mouse 同种型 IgG1 品种反应性 Human 抗体类型 Monoclonal Antibody 基因符号 - PP1alpha
- PP-1A
- PPP1A
纯化方法 Unpurified UniProt编号 - P62136
产品使用声明 质量保证 Evaluated by Western Blotting in HeLa, HepG2, MCF-7, Jurkat, and A549 cell lysates.
Western Blotting Analysis: A 1:500-2,000 dilution of this antibody detected PPP1CA in HeLa, HepG2, MCF-7, Jurkat, and A549 cell lysates.
Optimal working dilutions must be determined by end user.
使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.包装信息 数量 100 µL
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