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merck millipore,默克密理博,MABN673,Anti-ARNTL Antibody, clone 1C5
产品名称：Anti-ARNTL Antibody, clone 1C5
产品型号：MABN673
Anti-ARNTL Antibody, clone 1C5 is a highly specific mouse monoclonal antibody, that targets ARNT-Like 1 & has been tested in western blotting & IHC.
merck millipore,默克密理博,MABN673,Anti-ARNTL Antibody, clone 1C5
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H IHC, WB M Ascites Monoclonal Antibody 描述 产品目录编号 MABN673 描述 Anti-ARNTL Antibody, clone 1C5 Alternate Names - bHLH-PAS protein JAP3
- Aryl hydrocarbon receptor nuclear translocator-like protein 1
- Basic-helix-loop-helix-PAS protein MOP3
- Brain and muscle ARNT-like 1
- Class E basic helix-loop-helix protein 5
- Short name=bHLHe5
- Member of PAS protein 3
- PAS domain-containing protein 3
背景信息 Aryl hydrocarbon receptor nuclear translocator-like protein 1 or alternatively, Basic-helix-loop-helix PAS protein MOP3, Brain and muscle ARNT-like 1, Class E basic helix-loop-helix protein 5 (bHLHe5), Member of PAS protein 3, PAS domain-containing protein 3, bHLH-PAS protein JAP3, and encoded by the human gene ARNTL,BHLHE5, BMAL1, MOP3 or PASD3, is a protein belonging to the basic helix-loop-helix-PAS domain containing transcription factor family. ARNTL protein is important for the molecular mechanisms behind circadian rhythms as it interacts with a number of CLOCK (Circadian Locomotor Output Cycles Kaput) family members as well as CLOCK itself to promote transcription of a number of proteins of the circadian clock. ARNTL interacts with CRY and CRY2, PER, TIMELESS, and other clock related genes as well as non-CLOCK proteins such as HIF-1alpha (HIF1A) and SUMO3. ARNTL appears critical for proper function of rhythms, as only knockouts of ARNTL in mice generate mice that have upset biological clocks and a shorter lifespan. ARNTL is highly expressed in the adult brain as well as skeletal muscle and heart and ARNTL is a nuclear localized transcription activator. EMD-Millipore’s Anti-ARNTL mouse monoclonal antibody has been tested in western blot against recombinant transfected protein and in paraffin embedded immunohistochemistry on human spleen tissue sections. 产品信息 格式 Ascites 控制 - ARNTL-hIgGFc transfected HEK293 cell lysate
演示 Mouse monoclonal IgG1 ascitic fluid containing up to 0.1% sodium azide. 应用 应用 Anti-ARNTL Antibody, clone 1C5 is a highly specific mouse monoclonal antibody, that targets ARNT-Like 1 & has been tested in western blotting & IHC. 主要应用 - Immunohistochemistry
- Western Blotting
应用说明 Immunohistochemistry Analysis: A 1:200-1,000 dilution from a representative lot detected ARNTL in human spleen tissue.
Optimal working dilutions must be determined by end user.
生物信息 免疫原品种 Purified recombinant fragment of human ARNTL expressed in E. Coli. 克隆 1C5 宿主 Mouse 同种型 IgG1 品种反应性 Human 抗体类型 Monoclonal Antibody 基因符号 - ARNTL
- TIC
- JAP3
- MOP3
- BMAL1
- PASD3
- BMAL1c
- bHLHe5
- MGC47515
纯化方法 Unpurified UniProt编号 - O00327
产品使用声明 质量保证 Evaluated by Western Blotting in ARNTL-hIgGFc transfected HEK293 cell lysate.
Western Blotting Analysis: A 1:500-2,000 dilution of this antibody detected ARNTL-hIgGFc transfected HEK293 cell lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.包装信息 数量 100 µL
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