merck millipore,默克密理博,MABN615,Anti-Pan-GRK Antibody, clone N145/20

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Merck Millipore 默克密理愽

品种反应性	主要应用	宿主	格式	抗体类型
M	WB	M	Purified	Monoclonal Antibody

描述
产品目录编号	MABN615
描述	Anti-Pan-GRK Antibody, clone N145/20
Alternate Names	G protein-coupled receptor kinase GRK5 G protein-coupled receptor kinase 5
背景信息	G protein-coupled receptor kinases (GRK) are serine/threonine kinases that phosphorylate a variety of G-protein-coupled receptors (GPCRs), specifically activated forms, including adrenergic receptors, muscarinic acetylcholine receptors, dopamine receptors and opioid receptors. GRK receptor phosphorylation initiates beta-arrestin-mediated receptor desensitization, internalization, and signaling events leading to their down-regulation.

产品信息
格式	Purified
控制	Mouse liver tissue lysate
演示	Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

应用
应用	Anti-Pan-GRK Antibody, clone N145/20 Cat. No. MABN615 is a highly specific mouse monoclonal antibody & that targets GRK & has been tested in western blotting.
主要应用	Western Blotting

生物信息
免疫原品种	Recombinant protein corresponding to the C-terminus of mouse Pan-GRK.
表位	C-terminus
克隆	N145/20
浓缩	Please refer to the Certificate of Analysis for the lot-specific concentration.
宿主	Mouse
特异性	This antibody recognizes the C-terminus of GRK. This antibody cross reacts with GRK6 (Prof. J. Trimmer, University of California, Davis.).
同种型	IgG1κ
品种反应性	Mouse
抗体类型	Monoclonal Antibody
Entrez基因编号	NP_061357
基因符号	Gprk5 Grk5
纯化方法	Protein G purified
UniProt编号	Q8VEB1

产品使用声明
质量保证	Evaluated by Western Blotting in mouse liver tissue lysate. Western Blotting Analysis: 0.5 µg/mL of this antibody detected Pan-GRK in 10 µg of mouse liver tissue lysate.
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Stable for 1 year at 2-8°C from date of receipt.

包装信息
数量	100 µg

merck millipore,默克密理博,MABN615,Anti-Pan-GRK Antibody, clone N145/20

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