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merck millipore,默克密理博,MABN130,Anti-SQSTM1 Antibody, clone 20F1.1
产品名称：Anti-SQSTM1 Antibody, clone 20F1.1
产品型号：MABN130
Anti-SQSTM1 Antibody, clone 20F1.1 is a highly specific mouse monoclonal antibody, that targets p62 & has been tested in western blotting & IHC.
merck millipore,默克密理博,MABN130,Anti-SQSTM1 Antibody, clone 20F1.1
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H, R IHC, WB M Purified Monoclonal Antibody 描述 产品目录编号 MABN130 描述 Anti-SQSTM1 Antibody, clone 20F1.1 Alternate Names - Ubiquitin-binding protein p62
- Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa
- p60
- EBIAP
- EBI3-associated protein of 60 kDa
- Sequestosome-1
背景信息 Ubiquitin-binding protein p62, also known as Sequestosome-1 (SQSTM1), is a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-κB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-κB in response to upstream signals. Defects in p62/SQSTM1 are a cause of Paget disease of bone (PDB), a metabolic bone disease affecting the axial skeleton and characterized by focal areas of increased and disorganized bone turn-over due to activated osteoclasts 产品信息 格式 Purified 控制 - Rat brain tissue lysate
演示 Purified mouse monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 Anti-SQSTM1 Antibody, clone 20F1.1 is a highly specific mouse monoclonal antibody, that targets p62 & has been tested in western blotting & IHC. 主要应用 - Immunohistochemistry
- Western Blotting
应用说明 Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected SQSTM1 in human thalamus and human cerebellum tissue. 生物信息 免疫原品种 GST-tagged recombinant protein corresponding to human SQSTM1. 克隆 20F1.1 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Mouse 同种型 IgG2aκ 品种反应性 HumanRat 抗体类型 Monoclonal Antibody Entrez基因编号 - NP_001135770
基因符号 - OSIL
- SQSTM1
- ORCA
纯化方法 Protein G purified UniProt编号 - Q13501
产品使用声明 质量保证 Evaluated by Western Blotting in rat brain tissue lysate.
Western Blotting Analysis: 1.0 µg/mL of this antibody detected SQSTM1 in 10 µg of rat brain tissue lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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