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经验配方 CAS号 C₇₉H₁₃₁N₃₁O₂₄S₄ 24345-16-2 描述 概述 Polypeptide neurotoxin known to pass through the blood-brain barrier. Blocks the AHP-type Ca2+-activated K+ channel; does not block the TEA and voltage-sensitive Ca2+-activated K+ channel. Reported to induce neurodegeneration of Purkinje cells in rat brain. Known to induce the secretion of prolactin in a dose-dependent manner. 产品目录编号 178270 品牌系列 Calbiochem®
同义词 CNCKAPETALCARRCQQH-NH₂ 参考 参考 Mourre, C., et al. 1997. Brain Res. 778, 405.
Silva, E.G., et al. 1994. Br. J. Pharmacol. 113, 1022.
Wang, X., et al. 1994. Brain Res. 662, 83.产品信息 CAS号 24345-16-2 具有ATP竞争性 N 形式 White solid with dark tan cast Hill配方 C₇₉H₁₃₁N₃₁O₂₄S₄ 化学配方 C₇₉H₁₃₁N₃₁O₂₄S₄ Molar Mass 2027.3 吸湿 Hygroscopic
肽序列 H-Cys¹-Asn-Cys³-Lys-Ala-Pro-Glu-Thr-Ala-Leu-Cys¹¹-Ala-Arg-Arg-Cys¹⁵-Gln-Gln-His-NH₂ (disulfide bonds: 1 → 11; 3 → 15) 可逆 N 生物信息 主靶 AHP-type Ca2+-activated K+ channel 纯度 ≥98% by HPLC 理化信息 细胞可渗透 N 溶解度 5% Acetic Acid 肽序列 H-Cys¹-Asn-Cys³-Lys-Ala-Pro-Glu-Thr-Ala-Leu-Cys¹¹-Ala-Arg-Arg-Cys¹⁵-Gln-Gln-His-NH₂ (disulfide bonds: 1 → 11; 3 → 15) GHS安全信息 RTECS CD6899900 安全信息 R相 R: 20/21/22
Harmful by inhalation, in contact with skin and if swallowed.S相 S: 36
Wear suitable protective clothing.储存和货运信息 货运代码 Ambient Temperature Only
毒性 Harmful
储存 -20°C
吸湿 Hygroscopic
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze (-20°C). Acetic acid stock solutions are stable for up to 3 days at -20°C.
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