• merck millipore,默克密理博,178270,Apamin, Bee Venom - CAS 24345-16-2 - Calbiochem
  • merck millipore,默克密理博,178270,Apamin, Bee Venom - CAS 24345-16-2 - Calbiochem

    产品名称:Apamin, Bee Venom - CAS 24345-16-2 - Calbiochem
    产品型号:178270
    Polypeptide neurotoxin known to pass through the blood-brain barrier.

    merck millipore,默克密理博,178270,Apamin, Bee Venom - CAS 24345-16-2 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,178270,Apamin, Bee Venom - CAS 24345-16-2 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₇₉H₁₃₁N₃₁O₂₄S₄24345-16-2
    描述
    概述 Polypeptide neurotoxin known to pass through the blood-brain barrier. Blocks the AHP-type Ca2+-activated K+ channel; does not block the TEA and voltage-sensitive Ca2+-activated K+ channel. Reported to induce neurodegeneration of Purkinje cells in rat brain. Known to induce the secretion of prolactin in a dose-dependent manner.
    产品目录编号 178270
    品牌系列 Calbiochem®
    同义词 CNCKAPETALCARRCQQH-NH₂
    参考
    参考 Mourre, C., et al. 1997. Brain Res. 778, 405.
    Silva, E.G., et al. 1994. Br. J. Pharmacol. 113, 1022.
    Wang, X., et al. 1994. Brain Res. 662, 83.
    产品信息
    CAS号 24345-16-2
    具有ATP竞争性 N
    形式 White solid with dark tan cast
    Hill配方 C₇₉H₁₃₁N₃₁O₂₄S₄
    化学配方 C₇₉H₁₃₁N₃₁O₂₄S₄
    Molar Mass 2027.3
    吸湿 Hygroscopic
    肽序列 H-Cys¹-Asn-Cys³-Lys-Ala-Pro-Glu-Thr-Ala-Leu-Cys¹¹-Ala-Arg-Arg-Cys¹⁵-Gln-Gln-His-NH₂ (disulfide bonds: 1 → 11; 3 → 15)
    可逆 N
    生物信息
    主靶 AHP-type Ca2+-activated K+ channel
    纯度 ≥98% by HPLC
    理化信息
    细胞可渗透 N
    溶解度 5% Acetic Acid
    肽序列 H-Cys¹-Asn-Cys³-Lys-Ala-Pro-Glu-Thr-Ala-Leu-Cys¹¹-Ala-Arg-Arg-Cys¹⁵-Gln-Gln-His-NH₂ (disulfide bonds: 1 → 11; 3 → 15)
    GHS安全信息
    RTECS CD6899900
    安全信息
    R相 R: 20/21/22

    Harmful by inhalation, in contact with skin and if swallowed.
    S相 S: 36

    Wear suitable protective clothing.
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Harmful
    储存 -20°C
    吸湿 Hygroscopic
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Acetic acid stock solutions are stable for up to 3 days at -20°C.

    merck millipore,默克密理博,178270,Apamin, Bee Venom - CAS 24345-16-2 - Calbiochem

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