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merck millipore,默克密理博,MABE537,Anti-BANF1 Antibody, clone EPR7669, rabbit monoclonal
产品名称：Anti-BANF1 Antibody, clone EPR7669, rabbit monoclonal
产品型号：MABE537
Please note that this product will not be available for sale after March 15, 2015. Please select one of the other antibodies against this target.
merck millipore,默克密理博,MABE537,Anti-BANF1 Antibody, clone EPR7669, rabbit monoclonal
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H IHC, WB Rb Unpurified Monoclonal Antibody 描述 产品目录编号 MABE537 描述 Anti-BANF1 Antibody, clone EPR7669, rabbit monoclonal Alternate Names - Breakpoint cluster region protein 1
- Barrier-to-autointegration factor
背景信息 Barrier-to-autointegration factor (BANF1, BAF), also known as Breakpoint cluster region protein 1 (BCRG1), plays a critical role chromatin organization as well as subsequent gene expression particularly in embryonic stem cells (ESCs) development where it is required to maintain self-renewal potential. BANF1 initial naming comes from its interaction with viral proteins during infection. Various retroviruses, including HIV-1, make use of BANF1 protein to protect their DNA from normal autointegration destruction functions, and thus allowing viral integration in the host DNA chromosome. BANF1 is localized primarily in the nucleus but can be found in the cytoplasm as well, but during mitosis it is specifically localized to the chromosomes. The protein can bind dsDNA and nuclear membrane proteins and is thought to also play a role in chromatin positioning with respect to the nuclear periphery. There appear to be multiple isoforms as well. EMD-Millipore’s Anti-BANF1 rabbit monoclonal antibody has been tested in western blot on HeLa, HepG2 and 293T human cell lysates and in immunohistochemistry on paraffin embedded thyroid gland carcinoma tissue. 产品信息 格式 Unpurified 控制 - HeLa, HepG2, and HEK293T cell lysates
演示 Rabbit monoclonal in buffer containing PBS with up to 0.1% sodium azide, 0.05% BSA, and 50% glycerol. 应用 应用 Please note that this product will not be available for sale after March 15, 2015. Please select one of the other antibodies against this target. 主要应用 - Immunohistochemistry
- Western Blotting
应用说明 Immunohistochemistry Analysis: A 1:100-250 dilution from a representative lot detected BANF1 in human thyroid gland carcinoma tissue.
Optimal working dilutions must be determined by end user.生物信息 免疫原品种 Synthetic peptide corresponding to residues in human BANF1. 克隆 EPR7669 宿主 Rabbit 品种反应性 Human 抗体类型 Monoclonal Antibody 基因符号 - BCRG1
- BANF1
- BAF
纯化方法 Unpurified UniProt编号 - O75531
产品使用声明 质量保证 Evaluated by Western Blotting in HeLa, HepG2, and HEK293T cell lysates.
Western Blotting Analysis: A 1:1,000-10,000 dilution of this antibody detected BANF1 in HeLa, HepG2, and HEK293T cell lysates.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.包装信息 数量 100 µL
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