merck millipore,默克密理博,208734,Calmodulin Binding Domain - CAS 115044-69-4

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Merck Millipore 默克密理愽

merck millipore,默克密理博,208734,Calmodulin Binding Domain - CAS 115044-69-4 - Calbiochem

经验配方	CAS号
C₁₀₃H₁₈₅N₃₁O₂₄S	115044-69-4

描述
概述	Potent calmodulin antagonist. Inhibits activation of calmodulin-dependent protein kinase II (IC₅₀ = 52 nM). Interacts with the catalytic core of CaM kinase II as a pseudosubstrate.
产品目录编号	208734
品牌系列	Calbiochem®
同义词	Calmodulin antagonist, CaM kinase II 290-309

参考
参考	James, P., et al. 1995. Trends Biochem. Sci. 20, 38. Mukherji, S., and Soderling, T.R. 1995. J. Biol. Chem. 270, 14062. Yazawa, M., et al. 1992. Biochemistry 31, 3171. Payne, M.E., et al. 1988. J. Biol. Chem. 263, 7190.

产品信息
CAS号	115044-69-4
具有ATP竞争性	N
形式	White lyophilized solid
配方	Supplied as a trifluoroacetate salt.
Hill配方	C₁₀₃H₁₈₅N₃₁O₂₄S
化学配方	C₁₀₃H₁₈₅N₃₁O₂₄S
Molar Mass	2274.3
吸湿	Hygroscopic
肽序列	H-Leu-Lys-Lys-Phe-Asn-Ala-Arg-Arg-Lys-Leu-Lys-Gly-Ala-Ile-Leu-Thr-Thr-Met-Leu-Ala-OH
可逆	N
基于肽含量售出	Yes

生物信息
主靶	Calmodulin dependent Protein Kinase-2
主靶IC₅₀	52 nM against calmodulin-dependent protein kinase II
纯度	≥95% by HPLC

理化信息
细胞可渗透	N
溶解度	H₂O
肽含量	Yes
肽序列	H-Leu-Lys-Lys-Phe-Asn-Ala-Arg-Arg-Lys-Leu-Lys-Gly-Ala-Ile-Leu-Thr-Thr-Met-Leu-Ala-OH

储存和货运信息
货运代码	Ambient Temperature Only
毒性	Standard Handling
储存	-20°C
吸湿	Hygroscopic
无需冷冻	No
特殊指南	Following reconstitution, aliquot and freeze (-20°C). Aqueous stock solutions are stable for up to 1 year at -20°C.

merck millipore,默克密理博,208734,Calmodulin Binding Domain - CAS 115044-69-4 - Calbiochem

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