merck millipore,默克密理博,MABE513,Anti-TTF1, clone EPR5955(2), Rabbit Monoclonal Antibody

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merck millipore,默克密理博,MABE513,Anti-TTF1, clone EPR5955(2), Rabbit Monoclonal Antibody
产品名称：Anti-TTF1, clone EPR5955(2), Rabbit Monoclonal Antibody
产品型号：MABE513
Please note that this product will not be available for sale after March 15, 2015. Please select one of the other antibodies against this target.

merck millipore,默克密理博,MABE513,Anti-TTF1, clone EPR5955(2), Rabbit Monoclonal Antibody

产品介绍

merck millipore,默克密理博,MABE513,Anti-TTF1, clone EPR5955(2), Rabbit Monoclonal Antibody

重要规格表

品种反应性	主要应用	宿主	格式	抗体类型
M, H	IHC, WB	Rb	Unpurified	Monoclonal Antibody

描述
产品目录编号	MABE513
描述	Anti-TTF1, clone EPR5955(2), Rabbit Monoclonal Antibody
Alternate Names	TTF-1 Homeobox protein Nkx-2.1 Homeobox protein NK-2 homolog A Thyroid nuclear factor 1 Thyroid transcription factor 1
背景信息	Homeobox protein Nkx-2.1, also known as Homeobox protein NK-2 homolog A or Thyroid nuclear factor 1 or Thyroid transcription factor 1 (TTF-1), and encoded by the gene name NKX2-1 or TITF1 or TTF1, is a homeodomain-containing transcription factor that activates the transcriptional activity of thyroid-specific gene promoters by binding to them. Thyroid dysgenesis (TD) is responsible for most cases of congenital hypothyroidism, a condition that affects about one in 4000 newborns. Mutations in PAX8, TTF1, or FOXE1 may account for congenital hypothyroidism in patients with either isolated TD or TD with associated malformations involving kidney, lung, forebrain, and palate. In addition to its presence in thyroid gland epithelium, the human TTF1 protein was detected by immunohistochemistry in human fetal lung as early as 11 weeks of gestation, being localized in the nuclei of epithelial cells of the developing airways.

产品信息
格式	Unpurified
演示	Rabbit monoclonal in buffer containing PBS with up to 0.1% sodium azide, 0.05% BSA, and 50% glycerol.

应用
应用	Please note that this product will not be available for sale after March 15, 2015. Please select one of the other antibodies against this target.
主要应用	Immunohistochemistry Western Blotting
应用说明	Immunohistochemistry Analysis: A 1:250-500 dilution from a representative lot detected TTF1 in human lung adenocarcinoma tissue. Produced in collaboration with Epitomics™

生物信息
免疫原品种	Synthetic peptide corresponding to human TTF1.
克隆	EPR5955(2)
浓缩	Please refer to lot specific datasheet.
宿主	Rabbit
同种型	IgG
品种反应性	MouseHuman
Species Reactivity Note	Human, Mouse
抗体类型	Monoclonal Antibody
基因符号	TTF1 NKX2-1 NKX2A TITF1
纯化方法	Unpurified
UniProt编号	P43699

产品使用声明
质量保证	Evaluated by Western Blotting in HeLa, fetal lung and mouse lung lysates. Western Blotting Analysis: A 1:1,000-10,000 dilution of this antibody detected TTF1 in HeLa, fetal lung and mouse lung lysates.
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.

储存和货运信息

存储条件

Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.