merck millipore,默克密理博,MABE50,Anti-Phosphoepitope SR proteins Antibody, clone 1H4

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Merck Millipore 默克密理愽

品种反应性	主要应用	宿主	格式	抗体类型
H, R, M	ICC, WB	M	Purified	Monoclonal Antibody

描述
产品目录编号	MABE50
描述	Anti-Phosphoepitope SR proteins Antibody, clone 1H4
Alternate Names	Ser-Arg-rich proteins
背景信息	Ser-Arg-rich (SR) proteins make up a family of functionally and structurally conserved phosphoproteins, and are required components of alternative and constitutive pre-mRNA splicing. SR proteins are characterized by their modular composition consisting of two domains of interest: an N-terminal RNA recognition motif (RRM) which serves in the determination of DNA-binding specificity, and the RS domain, an arginine and serine rich, C-terminal domain that serves as a shuttling and localization director of SR proteins and as a splicing activation domain. They are involved in various aspects of pre-mRNA splicing and in spliceosome assembly including; the identification and appropriation of splice-sites, and the manipulation of alternative splicing regulation.

产品信息
格式	Purified
控制	L6 plus insulin cell lysate
演示	Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

应用
应用	Use Anti-Phosphoepitope SR proteins Antibody, clone 1H4 (Mouse Monoclonal Antibody) validated in WB, ICC, IP to detect Phosphoepitope SR proteins also known as Ser-Arg-rich proteins.
主要应用	Immunocytochemistry Western Blotting
应用说明	Immunocytochemistry Analysis: A representative lot was used by an independent laboratory in IC (Fukuhara, T., et al. (2006). Immunoprecipitation Analysis: A representative lot was used by an independent laboratory in IP (Buratti, E., et al. (2007).

生物信息
免疫原品种	Purified oocyte nuclei containing xenopus SR proteins.
克隆	1H4
浓缩	Please refer to the Certificate of Analysis for the lot-specific concentration.
宿主	Mouse
同种型	IgG1κ
品种反应性	HumanRatMouse
Species Reactivity Note	Demonstrated to react with rat. Predicted to react with mouse and human based on 100% sequence homology.
抗体类型	Monoclonal Antibody
基因符号	SR proteins
纯化方法	Protein G Purified

产品使用声明
质量保证	Evaluated by Western Blot in L6 plus insulin cell lysate. Western Blot Analysis: 0.025 µg/mL of this antibody detected SR proteins in 10 µg of L6 plus insulin cell lysate.
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Stable for 1 year at 2-8°C from date of receipt.

包装信息
数量	100 µg

merck millipore,默克密理博,MABE50,Anti-Phosphoepitope SR proteins Antibody, clone 1H4

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