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merck millipore,默克密理博,MABD175,Anti-SHH Antibody, clone 5H4
产品名称：Anti-SHH Antibody, clone 5H4
产品型号：MABD175
Anti-SHH Antibody, clone 5H4 is a highly specific mouse monoclonal antibody, that targets Sonic Hedgehog & has been tested in western blotting, Flow Cytometry & IHC.
merck millipore,默克密理博,MABD175,Anti-SHH Antibody, clone 5H4
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 Mk, H, M IHC, WB, FC M Purified Monoclonal Antibody 描述 产品目录编号 MABD175 描述 Anti-SHH Antibody, clone 5H4 Alternate Names - Sonic hedgehog protein
- HHG-1
背景信息 Sonic hedgehog protein (SHH) or alternatively known as HHG-1, is a very important developmental intercellular signaling factor. SHH protein is cleaved into to active forms, an N-terminal product that stays associated with the cell membrane or forms freely diffusible multimers and a C-terminal form that diffuses into the extracellular matrix. SHH is expressed in fetal intestine, liver, lung and kidney but not normally in adult tissues except during some disease state like cancerous tumors. The intercellular signaling triggered by SHH is essential for a variety of patterning events during development including the development of the notochord, neural tube and plate, as well as the polarizing of the anterior-posterior axis of developing limb buds. Because of its importance in patterning during development, defects in SHH are the cause of a number of abnormalities including structural eye and brain abnormalities, teeth and bone malformations and finally limb and bone developmental defects. EMD-Millipore’s Anti-SHH mouse monoclonal antibody has been tested in western blot against recombinant antigen and cell lysates from HepG2, PANC-1, HeLa, SK-N-SH, F9, NIH3T3 and COS7 cells and in paraffin embedded immunohistochemistry of human liver cancer tissue sections. The antibody has also been successfully tested by flow cytometry against HeLa cells in culture. 产品信息 格式 Purified 控制 - LNCaP, HepG2, PANC-1, HeLa, SK-N-SH, F9, NIH3T3, COS7 cell lysates
演示 Purified mouse monoclonal in PBS with up to 0.1% sodium azide and 0.05% protein stabilizer. 应用 应用 Anti-SHH Antibody, clone 5H4 is a highly specific mouse monoclonal antibody, that targets Sonic Hedgehog & has been tested in western blotting, Flow Cytometry & IHC. 主要应用 - Immunohistochemistry
- Western Blotting
- Flow Cytometry
应用说明 Immunohistochemistry Analysis: A 1:200-1,000 dilution from a representative lot detected SHH in liver cancer tissue.
Flow Cytometry Analysis: A 1:200-400 dilution from a representative lot detected SHH in non serum starved HeLa cells.
Optimal working dilutions must be determined by end user.生物信息 免疫原品种 Purified recombinant fragment of human SHH expressed in E. Coli. 克隆 5H4 宿主 Mouse 同种型 IgG1 品种反应性 MonkeyHumanMouse 抗体类型 Monoclonal Antibody 基因符号 - MCOPCB5
- SHH
- TPT
- HHG1
- HLP3
- HPE3
- SMMCI
- TPTPS
纯化方法 Protein G purified 产品使用声明 质量保证 Evaluated by Western Blotting in LNCaP, HepG2, PANC-1, HeLa, SK-N-SH, F9, NIH3T3, COS7 cell lysates.
Western Blotting Analysis: A 1:500-2,000 dilution of this antibody detected SHH in LNCaP, HepG2, PANC-1, HeLa, SK-N-SH, F9, NIH3T3, COS7 cell lysates.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µL
上一件merck millipore产品：merck millipore,默克密理博,324378,Domoic Acid, Mytilus edulis - CAS 14277-97-5 - Calbiochem
下一件merck millipore产品：merck millipore,默克密理博,13-124,IRS1
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