merck millipore,默克密理博,324378,Domoic Acid, Mytilus edulis - CAS 14277-97-5

搜索"Merck Millipore 密理愽"产品

Merck Millipore 默克密理愽

当前位置：首页 > >Merck Millipore > 生命科学研究
生命科学研究

merck millipore,默克密理博,324378,Domoic Acid, Mytilus edulis - CAS 14277-97-5 - Calbiochem
产品名称：Domoic Acid, Mytilus edulis - CAS 14277-97-5 - Calbiochem
产品型号：324378
A heat-stable neurotoxin.

merck millipore,默克密理博,324378,Domoic Acid, Mytilus edulis - CAS 14277-97-5 - Calbiochem

产品介绍

merck millipore,默克密理博,324378,Domoic Acid, Mytilus edulis - CAS 14277-97-5 - Calbiochem

重要规格表

经验配方	CAS号
C₁₅H₂₁NO₆	14277-97-5

描述
概述	A heat-stable neurotoxin. Glutamate kainate receptor agonist that shows higher affinity for the kainate receptor than any other known kainic acid analog. Causes excessive excitation of neurons resulting in the depletion of energy stores, cellular edema, and death. Inhibits adenylate cyclase activity in neuronal membranes. Evokes Ca²⁺-dependent and Ca²⁺-independent release of GABA.
产品目录编号	324378
品牌系列	Calbiochem®
同义词	25-[2α, 3β, 4β (1Z, 3E, 5R)]-2-Carboxy-4-(5-carboxy-1-methyl-1,3-hexadienyl)-3-pyrrolidineacetic Acid

参考
参考	Alfonso, M., et al. 1994. Neurochem. Int. 24, 267. Nijjar, M.S., and Grimmelt, B. 1994. Mol. Cell. Biochem. 136, 105. Hampson, D.R., et al. 1992. Eur. J. Pharmacol. 218, 1. Usherwood, P.N., and Barnard, E.A. 1992. Comp. Biochem. Physiol. [C] 103, 19. Tasker, R.A.R., et al. 1991. Can. J. Physiol. Pharmacol. 69, 127. Stewart, G.R., et al. 1990. Exp. Neurol. 110, 127. Bird, C.J., and Wright, J.L.C. 1989. World Aquacult. 20, 40. Wright, P., et al. 1989. Can. J. Chem. 67, 481.

参考

Alfonso, M., et al. 1994. Neurochem. Int. 24, 267.
Nijjar, M.S., and Grimmelt, B. 1994. Mol. Cell. Biochem. 136, 105.
Hampson, D.R., et al. 1992. Eur. J. Pharmacol. 218, 1.
Usherwood, P.N., and Barnard, E.A. 1992. Comp. Biochem. Physiol. [C] 103, 19.
Tasker, R.A.R., et al. 1991. Can. J. Physiol. Pharmacol. 69, 127.
Stewart, G.R., et al. 1990. Exp. Neurol. 110, 127.
Bird, C.J., and Wright, J.L.C. 1989. World Aquacult. 20, 40.
Wright, P., et al. 1989. Can. J. Chem. 67, 481.

产品信息
CAS号	14277-97-5
具有ATP竞争性	N
形式	White to off-white crystaline solid
Hill配方	C₁₅H₂₁NO₆
化学配方	C₁₅H₂₁NO₆
Molar Mass	311.3
可逆	N
结构配方图像

生物信息
主靶	Glutamate kainate receptor
纯度	≥95% by HPLC

理化信息
细胞可渗透	N
溶解度	H₂O or MeOH

GHS安全信息
RTECS	UX9665100

安全信息
R相	R: 20/21/22 Harmful by inhalation, in contact with skin and if swallowed.
S相	S: 36 Wear suitable protective clothing.

储存和货运信息
货运代码	Ambient Temperature Only
毒性	Harmful
储存	-20°C
无需冷冻	No
特殊指南	Following reconstitution, store in the refrigerator (4°C). Do not freeze solutions. Stock solutions are stable for up to 24 h at 4°C.