merck millipore,默克密理愽
  • merck millipore,默克密理博,MABC679,Anti-RUNX1 Antibody, clone 2B5

  • merck millipore,默克密理博,MABC679,Anti-RUNX1 Antibody, clone 2B5

    产品名称：Anti-RUNX1 Antibody, clone 2B5
    产品型号：MABC679
    Anti-RUNX1 Antibody, clone 2B5 is a highly specific mouse monoclonal antibody & that targets RUNX & has been tested in western blotting.

    merck millipore,默克密理博,MABC679,Anti-RUNX1 Antibody, clone 2B5

  • 产品介绍
  • merck millipore,默克密理博,MABC679,Anti-RUNX1 Antibody, clone 2B5

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    HWBMAscitesMonoclonal Antibody
    描述
    产品目录编号 MABC679
    描述 Anti-RUNX1 Antibody, clone 2B5
    Alternate Names
    • SL3/AKV core-binding factor alpha B subunit
    • Runt-related transcription factor 1
    • Acute myeloid leukemia 1 protein
    • Core-binding factor subunit alpha-2
    • CBF-alpha-2<br />Oncogene AML-1
    • Polyomavirus enhancer-binding protein 2 alpha B subunit
    • PEA2-alpha B
    • PEBP2-alpha B
    • SL3-3 enhancer factor 1 alpha B subunit
    背景信息 Runt-related transcription factor 1 (RUNX1), also known as Acute myeloid leukemia 1 protein, Core-binding factor subunit alpha-2 (CBF-alpha2), Oncogene AML-1, Polyomavirus enhancer-binding protein 2 alpha B subunit (PEA2-alpha B/PEBP2-alpha B), SL3-3 enhancer factor 1 alpha B subunit, and SL3/AKV core-binding factor alpha B subunit is encoded by the human gene named RUNX1/AML1, CBFA2. RUNX1 is a transcription factor that binds to a wide variety of promoters and enhancers belonging to many types of genes from T cell receptor genes to LCK, IL-3 and GM-CSF. Its major normal role is in the development of blood cells and hematopoiesis. It is expressed in most tissues except in normal brain and heart. Levels are highest in the bone marrow, thymus and peripheral lymphocytes. Defects and or translocations involving RUNX1 are the cause for myeloid leukemias as well as lymphoblastic leukemia. Mutations in RUNX1 function are also linked with many breast cancers. Finally, mutations in RUNX1 have recently been shown to be the cause of cancers in epithelial tissues and linked to squamous cell carcinomas. EMD-Millipore’s Anti-RUNX1 mouse monoclonal antibody has been tested in western blot on Jurkat cell lysates and in ELISA using recombinant RUNX1 protein.
    产品信息
    格式 Ascites
    控制
    • Jurkat cell lysate
    演示 Mouse monoclonal IgG1 ascitic fluid containing up to 0.1% sodium azide.
    应用
    应用 Anti-RUNX1 Antibody, clone 2B5 is a highly specific mouse monoclonal antibody & that targets RUNX & has been tested in western blotting.
    主要应用
    • Western Blotting
    生物信息
    免疫原品种 Synthesized peptide of human RUNX1.
    克隆 2B5
    宿主 Mouse
    同种型 IgG1
    品种反应性 Human
    抗体类型 Monoclonal Antibody
    基因符号
    • CBFA2
    • RUNX1
    • AML1
    纯化方法 Unpurified
    UniProt编号
    • Q01196
    产品使用声明
    质量保证 Evaluated by Western Blotting in Jurkat cell lysate.

    Western Blotting Analysis: A 1:500-2,000 dilution of this antibody detected RUNX1 in Jurkat cell lysate.

    Optimal working dilutions must be determined by end user.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Stable for 1 year at -20°C from date of receipt.
    Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
    包装信息
    数量 100 µL

    merck millipore,默克密理博,MABC679,Anti-RUNX1 Antibody, clone 2B5

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