merck millipore,默克密理愽
  • merck millipore,默克密理博,557403,RNA Polymerase III Inhibitor - CAS 577784-91-9 - Calbiochem

  • merck millipore,默克密理博,557403,RNA Polymerase III Inhibitor - CAS 577784-91-9 - Calbiochem

    产品名称：RNA Polymerase III Inhibitor - CAS 577784-91-9 - Calbiochem
    产品型号：557403
    The RNA Polymerase III Inhibitor, also referenced under CAS 577784-91-9, controls the biological activity of RNA Polymerase III. This small molecule/inhibitor is primarily used for Cell Structure appl More>>

    merck millipore,默克密理博,557403,RNA Polymerase III Inhibitor - CAS 577784-91-9 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,557403,RNA Polymerase III Inhibitor - CAS 577784-91-9 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₁₉H₁₅Cl₂N₃O₂S₂577784-91-9
    描述
    概述 A cell-permeable indazolo-sulfonamide compound that displays broad-spectrum inhibitory activity against RNA Polymerase III (IC50 = 27 and 32 µM for human and S. cerevisiae RNA Pol III, respectively). Inhibits cell growth in yeast by preventing RNA Pol III-mediated tRNA transcription. Also available as a 25 mM solution in DMSO (Cat. No. 557404).
    产品目录编号 557403
    品牌系列 Calbiochem®
    同义词 ML-60218, N-[1-(3-(5-Chloro-3-methylbenzo[b]thiophen-2-yl-1-methyl-1H-pyrazol-5-yl)]-2-chlorobenzenesulfonamide
    参考
    参考 Wu, L., et al. 2003. Euk. Cell 2, 256.
    产品信息
    CAS号 577784-91-9
    具有ATP竞争性 N
    形式 Off-white solid
    Hill配方 C₁₉H₁₅Cl₂N₃O₂S₂
    化学配方 C₁₉H₁₅Cl₂N₃O₂S₂
    Molar Mass 452.4
    可逆 N
    结构配方图像
    生物信息
    主靶 activity against RNA Polymerase III
    主靶IC50 27 and 32 µM for Human and S. cerevisiae RNA Pol III
    纯度 ≥95% by HPLC
    理化信息
    细胞可渗透 Y
    溶解度 DMSO
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Carcinogenic / Teratogenic
    储存 +2°C to +8°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,557403,RNA Polymerase III Inhibitor - CAS 577784-91-9 - Calbiochem

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