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merck millipore,默克密理博,MABC523,Anti-BCL7A Antibody, clone 15C
产品名称：Anti-BCL7A Antibody, clone 15C
产品型号：MABC523
Anti-BCL7A Antibody, clone 15C is a highly specific mouse monoclonal antibody, that targets B-cell CLL/lymphoma 7 protein family member A & has been tested in IHC & Immunofluorescence.
merck millipore,默克密理博,MABC523,Anti-BCL7A Antibody, clone 15C
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H IHC M Purified Monoclonal Antibody 描述 产品目录编号 MABC523 描述 Anti-BCL7A Antibody, clone 15C Alternate Names - B-cell CLL/lymphoma 7 protein family member A
背景信息 The protein named B-cell CLL/lymphoma 7 protein family member A or BCL7A and encoded by the human gene named BCL7A is protein that interacts with SWI/SNF components (a nucleosome remodeling complex), implicating that BCL7A’s normal function involves chromatin remodeling. BCL7A was original cloned from a chromosomal translocation in a Burkitt lymphoma cell line and appears to be important in B cell malignancy. Overexpression of BCL7A is associated with germinal center phenotype formation in B cells and BCL7A expression is up regulated in CLL and multiple myeloma but lower in mycosis fungoides and peripheral T cell lymphoma. Recent research indicates that BCL7A was expressed at the pro B and T cell stage and persisted through the pre-B and mature B cell stages. BCL7A expression was maintained in late B cell differentiation but down-regulated in late plasma cells and mature T cells. In haematological malignancies, BCL7A protein was present in the majority of precursor and mature B cell lymphomas with increased expression amongst GC-related lymphomas. Mature T cell malignancies did not express BCL7A. 产品信息 格式 Purified 演示 Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 Anti-BCL7A Antibody, clone 15C is a highly specific mouse monoclonal antibody, that targets B-cell CLL/lymphoma 7 protein family member A & has been tested in IHC & Immunofluorescence. 主要应用 - Immunohistochemistry
应用说明 Immunofluorescence Analysis: A 1:10 dilution from a representative lot detected BCL7A in human tonsil tissue (Prof. G. Roncador, CNIO, Madrid).
Immunohistochemistry Analysis: A 1:500 dilution from a representative lot detected BCL7A in human lymph node, spleen, and thymus tissue (Prof. G. Roncador, CNIO, Madrid).
Immunohistochemistry Analysis: A representative lot detected BCL7A in HEK293 cells transfected with BCL7A, and not in HEK293 cells transfected with SPIB protein (Prof. G. Roncador, CNIO, Madrid).生物信息 免疫原品种 His-tagged recombinant protein corresponding to human BCL7A. 克隆 15C 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Mouse 同种型 IgG1κ 品种反应性 Human 抗体类型 Monoclonal Antibody Entrez基因编号 - NP_001019979
基因符号 - BCL7A
纯化方法 Protein G purified UniProt编号 - Q4VC05
产品使用声明 质量保证 Evaluated by Immunohistochemistry in human tonsil and colon tissues.
Immunohistochemistry Analysis: A 1:500 dilution of this antibody detected BCL7A in human tonsil and colon tissues.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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