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merck millipore,默克密理博,MABC291,Anti-PSMA Antibody, clone 3/A12
产品名称:Anti-PSMA Antibody, clone 3/A12
产品型号:MABC291
Anti-PSMA Antibody, clone 3/A12 is a highly specific mouse monoclonal antibody, that targets PSMA & has been tested in Flow Cytometry, western blotting, Immunofluorescence, Activity Assay & Inhibition More>>
merck millipore,默克密理博,MABC291,Anti-PSMA Antibody, clone 3/A12
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H ACT, FC, WB M Purified Monoclonal Antibody 描述 产品目录编号 MABC291 Replaces MABN1035 描述 Anti-PSMA Antibody, clone 3/A12 Alternate Names - Pteroylpoly-gamma-glutamate carboxypeptidase
- Glutamate carboxypeptidase 2
- Cell growth-inhibiting gene 27 protein
- Folate hydrolase 1
- Folylpoly-gamma-glutamate carboxypeptidase
- FGCP
- Glutamate carboxypeptidase II
- GCPII
- Membrane glutamate carboxypeptidase
- mGCP
- N-acetylated-alpha-linked acidic dipeptidase I
- NAALADase I
- Prostate-specific membrane antigen
- PSM
- PSMA
背景信息 Prostate-specific membrane antigen (PSMA), also known as Glutamate carboxypeptidase II (GCPII), Folate hydrolase 1 (FOLH1), and N-acetylated-alpha-linked acidic dipeptidase I (NAALADase I), is a member of the peptidase M28 family and is involved in prostate tumor progression. It is highly expressed in prostate epithelium and detected in urinary bladder, kidney, testis, ovary, fallopian tube, breast, adrenal gland, liver, esophagus, stomach, small intestine, colon, and brain (at protein level). Mutations in PSMA have been associated with prostate cancer and hyperhomocysteinemia. PSMA may be a possible marker for neurological disorders such as schizophrenia, Alzheimer's disease, and Huntington disease. 产品信息 格式 Purified 演示 Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 Anti-PSMA Antibody, clone 3/A12 is a highly specific mouse monoclonal antibody, that targets PSMA & has been tested in Flow Cytometry, western blotting, Immunofluorescence, Activity Assay & Inhibition. 主要应用 - Activity Assay
- Flow Cytometry
- Western Blotting
应用说明 Western Blotting Analysis: A representative lot from an independent laboratory detected purified PSMA in WB (Elsasser-Beile, U., et al. (2006). Prostate. 66(13):1359-1370.).
Immunofluorescence Analysis: A representative lot from an independent laboratory detected PSMA in LNCaP cells (Elsasser-Beile, U., et al. (2006). Prostate. 66(13):1359-1370.).
Inhibition Assay Analysis (Small-animal PET imaging): A representative lot from an independent laboratory blocked PSMA in mice bearing PSMA-positive C4-2 tumors and negative DU145 tumors (Elsasser-Beile, U., et al. (2009). J Nucl Med. 50(4):606-611.).
Activity Assay Analysis: A representative lot from an independent laboratory was co-internalized with cell adherent PSMA, when PSMA binds to its putative ligand (Liu, J. et al. (2009). Mol Pharm. 6(3):959-970.).生物信息 免疫原品种 Recombinant protein corresponding to human PSMA. 克隆 3/A12 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Mouse 同种型 IgG1κ 品种反应性 Human 抗体类型 Monoclonal Antibody Entrez基因编号 - NP_001014986
基因符号 - PSMA
- FOLH1
- FOLH
- NAALAD1
- PSM
纯化方法 Protein G purified UniProt编号 - Q04609
产品使用声明 质量保证 Evaluated by Flow Cytometry in 1X10E6 LNCaP cells.
Flow Cytometry Analysis: 1 µg of this antibody detected PSMA in LNCaP cells.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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