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品种反应性 主要应用 宿主 格式 抗体类型 H WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABT181 Replaces MABT467 描述 Anti-DSG2 Antibody Alternate Names - HDGC
- Desmoglein-2
- Cadherin family member 5
背景信息 Desmoglein-2 (DSG2) is a single-pass type I membrane protein. Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Desmosomal cadherins, consisting of four desmogleins (DSG1-4) and three desmocollins (DSC1-3) in humans, mediate adhesion through calcium-dependent homophilic/heterophilic interactions. DSG2 is widely expressed in epithelial and non-epithelial tissues such as the intestine, epidermis, testis, and heart. Mutations in DSG2 have been associated with familial arrhythmogenic right ventricular dysplasia type 10 (ARVD10) and cardiomyopathy dilated type 1BB (CMD1BB). 产品信息 格式 Affinity Purified 控制 - HepG2 cell lysate
演示 Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 Detect Desmoglein using this rabbit polyclonal antibody, Anti-DSG2 Antibody validated for use in western blotting & IP. 主要应用 - Western Blotting
应用说明 Immunoprecipitation Analysis: A representative lot immunoprecipitated DSG2 from HepG2 cell lysate. 生物信息 免疫原品种 KLH-conjugated linear peptide corresponding to human DSG2 near the C-terminus. 表位 Near C-terminus 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 特异性 This antibody recognizes DSG2 near the C-terminus. 品种反应性 Human 抗体类型 Polyclonal Antibody Entrez基因编号 - NP_001934
基因符号 - CDHF5
- DSG2
纯化方法 Antigen Affinity purified UniProt编号 - Q14126
产品使用声明 质量保证 Evaluated by Western Blotting in HepG2 cell lysate.
Western Blotting Analysis: 0.25 µg/mL of this antibody detected DSG2 in 10 µg of HepG2 cell lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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下一件merck millipore产品：merck millipore,默克密理博,MAB5488,Anti-CRABP2 Antibody
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