merck millipore,默克密理愽
  • merck millipore,默克密理博,23-022,UbcH3 Protein, active, 10 µg

  • merck millipore,默克密理博,23-022,UbcH3 Protein, active, 10 µg

    产品名称：UbcH3 Protein, active, 10 µg
    产品型号：23-022
    Active, full length, recombinant human UbcH3. N-terminal HA, 6His-tagged. For use in Enzyme Assays. Functions as an E2 enzyme in ubiquitination assays.

    merck millipore,默克密理博,23-022,UbcH3 Protein, active, 10 µg

  • 产品介绍
  • merck millipore,默克密理博,23-022,UbcH3 Protein, active, 10 µg

    重要规格表

    主要应用 品种 级联部件
    EAHumanE2
    描述
    产品目录编号 23-022
    品牌系列 Upstate
    商名
    • Upstate
    描述 UbcH3 Protein, active, 10 µg
    长描述 N-terminal HA, 6His-tagged, recombinant human UbcH3 full length, expressed in E.coli.
    Alternate Names
    • Ubiquitin-protein ligase R1
    • Ubiquitin-conjugating enzyme E2 R1
    • E2-CDC34
    • UBE2R1
    • CDC34
    背景信息 Ubiquitin-conjugating (E2) enzymes are characterized by the presence of a highly conserved ubiquitin-conjugating domain which accommodates ATP-activated ubiquitin (Ub) via a covalently linked thioester onto its active-site residue. E2 enzymes act via selective protein-protein interactions with the ubiquitin-activating E1 enzyme and ubiquitin ligase E3 enzymes and are able to differentiate effects on downstream substrates, either with a single Ub molecule or an Ub chain. While E3s are involved in substrate selection, E2s are the main determinants for selection of the lysine to construct Ub chains, which thereby directly control the cellular fate of the substrate.
    UbcH3 has been shown to interact with a number of different E3 ligases, including SCFSkp2/Cks1, promoting the ubiquitination of p27 and SCFβTrCP1, promoting the ubiquitination of β-catenin and IκBα.
    应用
    应用 Active, full length, recombinant human UbcH3. N-terminal HA, 6His-tagged. For use in Enzyme Assays. Functions as an E2 enzyme in ubiquitination assays.
    主要应用
    • Enzyme Assay
    生物信息
    品种 Human
    特异活性 For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
    级联部件 E2
    Entrez基因编号
    • NM_004359 (GenBank Number)
    纯化方法 Purified using immobilized metal affinity chromatography.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    包装信息
    数量 10 µg

    merck millipore,默克密理博,23-022,UbcH3 Protein, active, 10 µg

上一件merck millipore产品：merck millipore,默克密理博,ABC261,Anti-CYP4F12 Antibody
下一件merck millipore产品：merck millipore,默克密理博,MZPHN0W10,MultiScreenHTS 384 PH，0.65 µm，不透明，非无菌


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