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merck millipore,默克密理博,IHCR1011-6,Anti-Synaptophysin Antibody, prediluted, clone SY38
产品名称:Anti-Synaptophysin Antibody, prediluted, clone SY38
产品型号:IHCR1011-6
Anti-Synaptophysin Antibody, prediluted, clone SY38 is an antibody against Synaptophysin for use in IH(P).
merck millipore,默克密理博,IHCR1011-6,Anti-Synaptophysin Antibody, prediluted, clone SY38
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 F, Av, B, H, M, R IH(P) M Purified Monoclonal Antibody 描述 产品目录编号 IHCR1011-6 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-Synaptophysin Antibody, prediluted, clone SY38 产品信息 格式 Purified 演示 Liquid diluted in PBS, pH 7.2 with stabilizers, 0.2% Tween 20, and 0.1% ProClin 300 as preservative. 应用 应用 Anti-Synaptophysin Antibody, prediluted, clone SY38 is an antibody against Synaptophysin for use in IH(P). 主要应用 - Immunohistochemistry (Paraffin)
应用说明 Antibody is prediluted and ready to use for Immunohistochemistry of formalin-fixed, paraffin-embedded tissues.
Pretreatment: Heat Induced Epitope Retrieval (HIER). Recommend Citrate Buffer, pH 6.0 (Cat. No. 21545). No signal was detected without Epitope retrieval.
Incubation: 30 minutes with IHC Select® Detection Kits.
Synaptophysin has been prediluted for use as the primary antibody with Chemicon's IHC Select® Detection Kits and Protocols (Catalog Nos. DAB050, DET-HP1000, APR050, and DET-APR1000), but other supplier's IHC detection systems may be used.生物信息 免疫原品种 Vesicular fraction of bovine brain. The SY38 epitope is to a pentapeptide repeat structure in the carboxy-terminal cytoplasmic tail of synaptophysin (Knaus & Betz 1990). 克隆 SY38 宿主 Mouse 特异性 The antibody reacts with presynaptic vesicles of cerebral and spinal neurons, of neuromuscular endplates and with the retina of man, cow, rat and mouse. The antibody also reacts with vesicles of adrenal medulla and islet cells, and additionally allows specific staining of neuronal, adrenal and neuroepithelial tumors, such as pheochromocytoma, paraganglioma, islet cell tumors (incl. insulinoma), medullary thyroid carcinoma and diverse pulmonary and gastro-intestinal carcinoids. The antibody also stains neurosecretory vesicles of certain culture cells, e.g. of the rat cell line PC-12. 同种型 IgG1κ 品种反应性 FishAvianBovineHumanMouseRat 抗体类型 Monoclonal Antibody Entrez基因编号 - NM_003179.2
Entrez基因汇总 Synaptophysin (p38) is an integral membrane protein of small synaptic vesicles in brain and endocrine cells.[supplied by OMIM] 基因符号 - Synaptophysin
- SYP
- synaptophysin
UniProt编号 - P08247
UniProt汇总 FUNCTION: SwissProt: P08247 # Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane.
SIZE: 313 amino acids; 33845 Da
SUBUNIT: Homohexamer or homotetramer.
SUBCELLULAR LOCATION: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein.
TISSUE SPECIFICITY: Characteristic of a type of small (30-80 nm) neurosecretory vesicles, including presynaptic vesicles, but also vesicles of various neuroendocrine cells of both neuronal and epithelial phenotype.
DOMAIN: SwissProt: P08247 The calcium-binding activity is thought to be localized in the cytoplasmic tail of the protein.
PTM: Ubiquitinated; mediated by SIAH1 or SIAH2 and leading to its subsequent proteasomal degradation (By similarity).
SIMILARITY: Belongs to the synaptophysin/synaptobrevin family. & Contains 1 MARVEL domain.产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain at 2-8°C. Refer to vial for expiration dating. 包装信息 数量 6 mL
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