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品种反应性 主要应用 宿主 格式 抗体类型 H WB M Purified Monoclonal Antibody 描述 产品目录编号 MABC276 描述 Anti-BAG3 Antibody, clone AC-2 Alternate Names - Docking protein CAIR-1
- BAG family molecular chaperone regulator 3
- Bcl-2-associated athanogene 3
- Bcl-2-binding protein Bis
背景信息 Bcl2-associated athanogene 3 (BAG3), also known as CAIR-1 or Bis, belongs to a family of six evolutionarily conserved co-chaperone proteins that contain a characteristic C-terminal BAG domain. In most cell types, BAG3 is localized to the cytoplasm, where it regulates the heat shock protein 70 chaperone. BAG3 is activated in response to stressful stimuli, and plays a critical role in modulating multiple cellular processes, including apoptosis, autophagy, embryonic development, and actin rearrangement. Abnormal expression of BAG3 results cardiomyopathy dilated type 1HH. 产品信息 格式 Purified 控制 - HeLa cell lysate
演示 Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 Anti-BAG3 Antibody, clone AC-2 detects level of BAG3 & has been published & validated for use in Western Blotting. 主要应用 - Western Blotting
应用说明 Immunoprecipitation Analysis: A 1:500 dilution from a representative lot detected BAG3 IP'd from 500 µg of HeLa lysate. 生物信息 免疫原品种 MAP peptide corresponding to human BAG3. 克隆 AC-2 宿主 Mouse 同种型 IgG1κ 品种反应性 Human Species Reactivity Note Demonstrated to react with Human. 抗体类型 Monoclonal Antibody Entrez基因编号 - NP_004272
基因符号 - BIS
- BAG3
纯化方法 Protein G purified UniProt编号 - O95817
产品使用声明 质量保证 Evaluated by Western Blot in HeLa cell lysate.
Western Blot Analysis: A 1:1000 dilution of this antibody detected BAG3 in 10 µg of HeLa cell lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µL
上一件merck millipore产品：merck millipore,默克密理博,538944,U-46619 - CAS 56985-40-1 - Calbiochem
下一件merck millipore产品：merck millipore,默克密理博,MABD125,Anti-LeX Glycan Antibody, clone Forse-1
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