merck millipore,默克密理愽
  • merck millipore,默克密理博,MAB5280X,Anti-Tyrosine Hydroxylase Antibody, clone 2/40/15, Alexa Fluor 488

  • merck millipore,默克密理博,MAB5280X,Anti-Tyrosine Hydroxylase Antibody, clone 2/40/15, Alexa Fluor 488

    产品名称：Anti-Tyrosine Hydroxylase Antibody, clone 2/40/15, Alexa Fluor 488
    产品型号：MAB5280X
    Anti-Tyrosine Hydroxylase Antibody, clone 2/40/15, Alexa Fluor 488 is an antibody against Tyrosine Hydroxylase for use in IH.

    merck millipore,默克密理博,MAB5280X,Anti-Tyrosine Hydroxylase Antibody, clone 2/40/15, Alexa Fluor 488

  • 产品介绍
  • merck millipore,默克密理博,MAB5280X,Anti-Tyrosine Hydroxylase Antibody, clone 2/40/15, Alexa Fluor 488

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    Qu, B, Ch, RIHCMAlexaFluor®488Monoclonal Antibody
    描述
    产品目录编号 MAB5280X
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Anti-Tyrosine Hydroxylase Antibody, clone 2/40/15, Alexa Fluor® 488
    产品信息
    格式 AlexaFluor®488
    演示 Purified immunoglobulin conjugated to Alexa Fluor® 488. Liquid in Phosphate buffer with 15 mg/mL BSA as a stabilizer and 0.1% sodium azide.
    应用
    应用 Anti-Tyrosine Hydroxylase Antibody, clone 2/40/15, Alexa Fluor 488 is an antibody against Tyrosine Hydroxylase for use in IH.
    主要应用
    • Immunohistochemistry
    应用说明 Immunohistochemistry

    Optimal working dilutions must be determined by end user.
    生物信息
    免疫原品种 Purified tyrosine hydroxylase (EC 1.14.16.2) from a rat pheochromocytoma (2).
    克隆 clone 2/40/15
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Mouse
    特异性 Tyrosine hydroxylase (TH) catalyzes the rate-determining initial step in the biosynthesis of catecholamines such as dopamine, noradrenaline and adrenaline. Therefore the antibody is used to stain dopaminergeous and adrenergeous neurons as well as the chromaffine tissue of the adrenal medulla. Cell lines such as the PC 12 line, which is derived from a rat pheochromocytoma also, show positive reactions. In immunoblots of adrenal medulla tissue, the antibody recognizes a single protein band in the molecular weight range of 56 - 60 kD.
    同种型 IgG2a
    品种反应性 QuailBovineChickenRat
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • NM_199293.2
    • NM_000360.3
    • NM_199292.2
    Entrez基因汇总 Tyrosine hydroxylase is involved in the conversion of tyrosine to dopamine. As the rate-limiting enzyme in the synthesis of catecholamines, tyrosine hydroxylase has a key role in the physiology of adrenergic neurons.
    基因符号
    • EC 1.14.16.2
    • TH
    • TYH
    UniProt编号
    • P07101
    UniProt汇总 FUNCTION: SwissProt: P07101 # Plays an important role in the physiology of adrenergic neurons.
    COFACTOR: Fe(2+) ion.
    SIZE: 528 amino acids; 58524 Da
    TISSUE SPECIFICITY: Mainly expressed in the brain and adrenal glands.
    DISEASE: SwissProt: P07101 # Defects in TH are the cause of autosomal recessive Segawa syndrome [MIM:605407]; also known as DOPA-responsive dystonia. Typically, it begins in childhood or adolescence with progressive difficulty in walking and, in some cases, spasticity. Some cases present with parkinsonian symptoms in infancy and are referred to as autosomal recessive infantile parkinsonism.
    SIMILARITY: SwissProt: P07101 ## Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    • Alexa Fluor® is a registered trademark of Molecular Probes, Inc.
    储存和货运信息
    存储条件 Maintain at 2-8°C in undiluted aliquots in the dark for up to 6 months after date of receipt.
    包装信息
    数量 100 µg

    merck millipore,默克密理博,MAB5280X,Anti-Tyrosine Hydroxylase Antibody, clone 2/40/15, Alexa Fluor 488

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