- 当前位置：首页 > >Merck Millipore > 生命科学研究
- 生命科学研究
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H IHC, FC, WB M Culture Supernatant Monoclonal Antibody 描述 产品目录编号 MAB4147 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-MRP1 Antibody, clone MRPm5 产品信息 格式 Culture Supernatant 演示 Tissue culture supernatant, serum-free. Liquid containing 0.7% BSA and 0.1% sodium azide. 应用 应用 Detect MRP1 using this Anti-MRP1 Antibody, clone MRPm5 validated for use in FC, WB, IH, IH(P). 主要应用 - Immunohistochemistry
- Flow Cytometry
- Western Blotting
应用说明 Western blotting
Immunohistochemistry: 1:20 on acetone fixed frozen tissue sections or paraffin-embedded tissue sections
Flow Cytometry
Optimal working dilutions must be determined by end user.生物信息 免疫原品种 Bacterial fusion protein of MRP1 containing amino acids 986-1204 of the protein. 克隆 MRPm5 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Mouse 特异性 This antibody reacts with an internal epitope of MRP1, a 180-195 kDa transmembrane transporter protein overexpressed in various human non-P-glycoprotein MDR tumor cell lines. The antibody does not cross-react with the human MDR1 and MDR3 gene products. 同种型 IgG2a 品种反应性 Human 抗体类型 Monoclonal Antibody Entrez基因编号 - NM_019900.2
- NM_019901.1
- NM_019902.1
- NM_004996.3
- NM_019862.2
- NM_019898.2
- NM_019899.2
Entrez基因汇总 The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts. Alternative splicing by exon deletion results in several splice variants but maintains the original open reading frame in all forms. 基因符号 - DKFZp686N04233
- ABCC1
- 4transporter)
- ABC29
- GS-X
- ABCC
- MRP1
- DKFZp781G125
- MRP
UniProt编号 - P33527
UniProt汇总 FUNCTION: SwissProt: P33527 # May participate directly in the active transport of drugs into subcellular organelles or influence drug distribution indirectly. Confers resistance to anticancer drugs. Transports LTC4. May protect milk against xenobiotics (By similarity).
SIZE: 1531 amino acids; 171561 Da
SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
TISSUE SPECIFICITY: Lung, testis and peripheral blood mononuclear cells.
SIMILARITY: SwissProt: P33527 ## Belongs to the ABC transporter family. Conjugate transporter (TC 3.A.1.208) subfamily. & Contains 2 ABC transmembrane type-1 domains. & Contains 2 ABC transporter domains.产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. May be stored at 2-8°C for short term use. Avoid repeated freeze-thaw cycles. 包装信息 数量 100 µg
上一件merck millipore产品：merck millipore,默克密理博,MABT62,Anti-Nectin-2/PVRL2 (CD112) Antibody, clone R2.525
下一件merck millipore产品：merck millipore,默克密理博,17-10156,LentiBrite™ α-actinin-GFP Lentiviral Biosensor
相关产品
merck millipore,默克密理博,NS145,Dopaminergic Neuron Integration and Characterization Kit
merck millipore,默克密理博,MABT14,Anti-Cytohesin-1 Antibody, clone 7H2
merck millipore,默克密理博,AP500F,Goat Anti-Mouse IgM µ chain Antibody, FITC conjugate, Species Adsorbed
merck millipore,默克密理博,MABN518,Anti-Tafazzin Antibody, clone N173B/13
merck millipore,默克密理博,MABT62,Anti-Nectin-2/PVRL2 (CD112) Antibody, clone R2.525
merck millipore,默克密理博,17-10156,LentiBrite™ α-actinin-GFP Lentiviral Biosensor
merck millipore,默克密理博,2910,Whole Cell Extraction Kit
merck millipore,默克密理博,MABF106,Anti-Viperin Antibody, clone MaP.VIP
merck millipore,默克密理博,MAB985,Anti-Echovirus 4 Antibody, clone 431-4H-6H-3B
merck millipore,默克密理博,56755,Sorbitol - CAS 50-70-4 - Calbiochem