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merck millipore,默克密理博,MAB4089,Anti-Prostate Cell Surface Antigen Antibody, clone 5E10
产品名称：Anti-Prostate Cell Surface Antigen Antibody, clone 5E10
产品型号：MAB4089
This Anti-Prostate Cell Surface Antigen Antibody, clone 5E10 is validated for use in FC, WB, IH for the detection of Prostate Cell Surface Antigen.
merck millipore,默克密理博,MAB4089,Anti-Prostate Cell Surface Antigen Antibody, clone 5E10
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H IHC, FC, WB M Purified Monoclonal Antibody 描述 产品目录编号 MAB4089 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-Prostate Cell Surface Antigen Antibody, clone 5E10 产品信息 格式 Purified 演示 Purified immunoglobulin. Liquid in 0.02M Phosphate buffer, 0.25M NaCl, pH=7.6 containing 0.1% sodium azide. 应用 应用 This Anti-Prostate Cell Surface Antigen Antibody, clone 5E10 is validated for use in FC, WB, IH for the detection of Prostate Cell Surface Antigen. 主要应用 - Immunohistochemistry
- Flow Cytometry
- Western Blotting
应用说明 Immunoblotting
Immunohistochemistry on fresh frozen tissues
Flow cytometry
Optimal working dilutions must be determined by the end user.生物信息 免疫原品种 Whole live cells of six human prostatic carcinoma cell lines, ALVA31, DU145, JCA1, LNCaP, ND1 and PC3. 克隆 5E10 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Mouse 特异性 Reacts with the cell surface transmembrane glycoprotein of human prostate epithelial cells (Cells were treated with phospholipase C and stained with MAB4089. The treatment did not decrease the MAB4089 staining). Molecular weight approximately 110 kDa. Reacts with both benign and malignant cells. Reacts with DU145, ND1, PC3 and ALV31 cell lines. No reactivity with LNCaP and JCA1 cell lines. The epitope that MAB4089 recognizes has not been determined. 同种型 IgG1 品种反应性 Human 抗体类型 Monoclonal Antibody Entrez基因编号 - NM_001648.2
- NM_001030047.1
- NM_001030048.1
- NM_001030049.1
- NM_001030050.1
Entrez基因汇总 Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms. 基因符号 - EC 3.4.21.77
- KLK3
- Seminin
- seminin
- APS
- hK3
- PSA
- semenogelase
- Semenogelase
- gamma-seminoprotein
- KLK2A1
- Gamma-seminoprotein
UniProt编号 - P07288
UniProt汇总 FUNCTION: SwissProt: P07288 # Hydrolyzes semenogelin-1 thus leading to the liquefaction of the seminal coagulum.
SIZE: 261 amino acids; 28741 Da
SUBCELLULAR LOCATION: Secreted.
SIMILARITY: SwissProt: P07288 ## Belongs to the peptidase S1 family. Kallikrein subfamily. & Contains 1 peptidase S1 domain.产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain at -20°C in undiluted aliquots for up to 12 months. 包装信息 数量 100 µg
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