• merck millipore,默克密理博,567305,SKF-86002 - CAS 72873-74-6 - Calbiochem
  • merck millipore,默克密理博,567305,SKF-86002 - CAS 72873-74-6 - Calbiochem

    产品名称:SKF-86002 - CAS 72873-74-6 - Calbiochem
    产品型号:567305
    A cell-permeable, reversible, and ATP-competitive cytokine-suppressive anti-inflammatory drug (CSAID).

    merck millipore,默克密理博,567305,SKF-86002 - CAS 72873-74-6 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,567305,SKF-86002 - CAS 72873-74-6 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₁₆H₁₂FN₃S72873-74-6
    描述
    概述 A cell-permeable, reversible, and ATP-competitive cytokine-suppressive anti-inflammatory drug (CSAID). A bicyclic imidazole that inhibits lipolysaccharide (LPS)-stimulated human monocyte IL-1 and TNF-α production (IC50 = 1 µM). Also acts as an inhibitor of both cyclooxygenase and 5-lipoxygenase. SKF-86002 also acts as a specific p38 MAP kinase inhibitor.
    产品目录编号 567305
    品牌系列 Calbiochem®
    同义词 6-(4-Fluorophenyl)-2,3-dihydro-5-(4-pyridyl)imidazo[2,1-b]thiazole
    参考
    参考 Frasch, S.C., et al. 1998. J. Biol. Chem. 273, 8389.
    Blanque, R., et al. 1997. Drugs Exp. Clin. Res. 23, 63.
    Lee, J.C., et al. 1995. Nature 372, 739.
    Prichett, W., et al. 1995. J. Inflamm. 45, 97.
    Lee, J.C., et al. 1993. Ann. N.Y. Acad. Sci. 696, 149.
    产品信息
    CAS号 72873-74-6
    具有ATP竞争性 Y
    形式 Off-white solid
    Hill配方 C₁₆H₁₂FN₃S
    化学配方 C₁₆H₁₂FN₃S
    Molar Mass 297.4
    可逆 Y
    结构配方图像
    生物信息
    主靶 (LPS)-stimulated IL-1 and TNF-α production
    主靶IC50 1 µM inhibiting lipolysaccharide (LPS)-stimulated human monocyte IL-1 and TNF-α production
    纯度 ≥95% by HPLC
    理化信息
    细胞可渗透 Y
    溶解度 DMSO
    安全信息
    R相 R: 36/37/38

    Irritating to eyes, respiratory system and skin.
    S相 S: 26-36

    In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
    Wear suitable protective clothing.
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Irritant
    储存 +2°C to +8°C
    避光 Protect from light
    无需冷冻 No

    merck millipore,默克密理博,567305,SKF-86002 - CAS 72873-74-6 - Calbiochem

上一件merck millipore产品:merck millipore,默克密理博,681640,Wee1 Inhibitor - CAS 622855-37-2 - Calbiochem
下一件merck millipore产品:merck millipore,默克密理博,MAB4089,Anti-Prostate Cell Surface Antigen Antibody, clone 5E10



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