• merck millipore,默克密理博,681640,Wee1 Inhibitor - CAS 622855-37-2 - Calbiochem
  • merck millipore,默克密理博,681640,Wee1 Inhibitor - CAS 622855-37-2 - Calbiochem

    产品名称:Wee1 Inhibitor - CAS 622855-37-2 - Calbiochem
    产品型号:681640
    The Wee1 Inhibitor, also referenced under CAS 622855-37-2, controls the biological activity of Wee1. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation application More>>

    merck millipore,默克密理博,681640,Wee1 Inhibitor - CAS 622855-37-2 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,681640,Wee1 Inhibitor - CAS 622855-37-2 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₂₀H₁₁ClN₂O₃622855-37-2
    描述
    概述 A pyrrolocarbazole compound that acts as a potent, ATP-binding site-targeting inhibitor of Wee1 (IC50 = 11 nM) in an ATP-competitive manner and displays ~40-fold selectivity over the related checkpoint kinase Chk1 (IC50 = 440 nM).
    产品目录编号 681640
    品牌系列 Calbiochem®
    同义词 4-(2-Chlorophenyl)-9-hydroxypyrrolo[3,4-c]carbazole-1,3-(2H,6H)-dione, Chk1 Inhibitor V
    参考
    参考 Palmer, B.D., et al. 2006. J. Med. Chem. 49, 4896.
    产品信息
    CAS号 622855-37-2
    具有ATP竞争性 Y
    形式 Light orange solid
    Hill配方 C₂₀H₁₁ClN₂O₃
    化学配方 C₂₀H₁₁ClN₂O₃
    Molar Mass 362.8
    可逆 N
    结构配方图像
    生物信息
    主靶 Wee1
    主靶IC50 11 nM
    纯度 ≥97% by HPLC
    理化信息
    细胞可渗透 N
    溶解度 DMSO or EtOH
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 -20°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,681640,Wee1 Inhibitor - CAS 622855-37-2 - Calbiochem

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