merck millipore,默克密理愽
  • merck millipore,默克密理博,MAB3842,Anti-Heat Shock Protein 25/27 Antibody

  • merck millipore,默克密理博,MAB3842,Anti-Heat Shock Protein 25/27 Antibody

    产品名称：Anti-Heat Shock Protein 25/27 Antibody
    产品型号：MAB3842
    Anti-Heat Shock Protein 25/27 Antibody detects level of Heat Shock Protein 25/27 & has been published & validated for use in IP, WB & IC.

    merck millipore,默克密理博,MAB3842,Anti-Heat Shock Protein 25/27 Antibody

  • 产品介绍
  • merck millipore,默克密理博,MAB3842,Anti-Heat Shock Protein 25/27 Antibody

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    Fe, B, Ca, Ch, Gt, H, M, Po, R, FICC, WBMPurifiedMonoclonal Antibody
    描述
    产品目录编号 MAB3842
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Anti-Heat Shock Protein 25/27 Antibody
    Alternate Names
    • HSP25/27
    产品信息
    格式 Purified
    演示 Purified immunoglobulin. Liquid in PBS, pH 7.4 containing 0.09% sodium azide.
    应用
    应用 Anti-Heat Shock Protein 25/27 Antibody detects level of Heat Shock Protein 25/27 & has been published & validated for use in IP, WB & IC.
    主要应用
    • Immunocytochemistry
    • Western Blotting
    应用说明 Western blot: suggested working concentration 5 μg/mL.

    Immunocytochemistry: suggested working concentration 0.1 mg/mL.

    Immunoprecipitation

    ELISA

    Optimal working dilutions must be determined by end user.
    生物信息
    免疫原品种 Recombinant chicken HSP25.
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Mouse
    特异性 Reacts with Heat Shock Protein 25 (HSP25).
    同种型 IgG2b
    品种反应性 FelineBovineCanineChickenGoatHumanMousePigRatFish
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • NM_001540.2
    基因符号
    • SRP27
    • HSPB1
    • HspB1
    • HS.76067
    • HMN2B
    • Hs.76067
    • HSP27
    • Hsp25
    • HSP28
    • CMT2F
    • DKFZp586P1322
    UniProt编号
    • P04792
    UniProt汇总 FUNCTION: SwissProt: P04792 # Involved in stress resistance and actin organization.
    SIZE: 205 amino acids; 22783 Da SUBUNIT: Interacts with TGFB1I1 (By similarity). Associates with alpha- and beta-tubulin and microtubules. Interacts with HSPB8 and HSPBAP1.
    SUBCELLULAR LOCATION: Cytoplasm. Nucleus. Note=Cytoplasmic in interphase cells. Colocalizes with mitotic spindles in mitotic cells. Translocates to the nucleus during heat shock.
    PTM: Phosphorylated in MCF-7 cells on exposure to protein kinase C activators and heat shock.
    DISEASE: SwissProt: P04792 # Defects in HSPB1 are the cause of Charcot-Marie-Tooth disease type 2F (CMT2F) [MIM:606595]. CMT2F is a form of Charcot- Marie-Tooth disease, the most common inherited disorder of the peripheral nervous system. Charcot-Marie-Tooth disease is classified in two main groups on the basis of electrophysiologic properties and histopathology: primary peripheral demyelinating neuropathy or CMT1, and primary peripheral axonal neuropathy or CMT2. Neuropathies of the CMT2 group are characterized by signs of axonal regeneration in the absence of obvious myelin alterations, normal or slightly reduced nerve conduction velocities, and progressive distal muscle weakness and atrophy. Nerve conduction velocities are normal or slightly reduced. CMT2F onset is between 15 and 25 years with muscle weakness and atrophy usually beginning in feet and legs (peroneal distribution). Upper limb involvement occurs later. CMT2F inheritance is autosomal dominant. & Defects in HSPB1 are a cause of distal hereditary motor neuropathy (dHMN) [MIM:608634]. Distal HMN is a pure motor peripheral neuropathy without sensory abnormalities.
    SIMILARITY: SwissProt: P04792 ## Belongs to the small heat shock protein (HSP20) family.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Maintain at 2-8°C in undiluted aliquots for up to 6 months after date of receipt.
    包装信息
    数量 100 µg

    merck millipore,默克密理博,MAB3842,Anti-Heat Shock Protein 25/27 Antibody

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