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品种反应性 主要应用 宿主 格式 抗体类型 Sal, H, Ht, Po, R IHC, WB M Ascites Monoclonal Antibody 描述 产品目录编号 MAB333 Replaces AB5863P 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-Synaptobrevin Antibody, clone SP10 Alternate Names - VAMP
产品信息 格式 Ascites 演示 Liquid, contains sodium azide. 应用 应用 Anti-Synaptobrevin Antibody, clone SP10 is an antibody against Synaptobrevin for use in WB, IH. 主要应用 - Immunohistochemistry
- Western Blotting
应用说明 Immunohistochemistry at >1:25.
Western blotting at 1:100-1:10,000.
Optimal working dilutions must be determined by the end user.生物信息 免疫原品种 Crude synaptic immunoprecipitate (Human). 克隆 SP10 宿主 Mouse 特异性 Synaptobrevin [VAMP]. MAB333 reacts with VAMP-1 and VAMP-2 fusion protein expressed in bacterial system. 同种型 IgM 品种反应性 SalamanderHumanHamsterPigRat 抗体类型 Monoclonal Antibody Entrez基因编号 - NM_199245.1
- NM_014231.3
- NM_016830.2
Entrez基因汇总 Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. VAMP1 is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Multiple alternative splice variants that encode proteins with alternative carboxy ends have been described, but the full-length nature of some variants has not been defined. 基因符号 - DKFZp686H12131
- VAMP1
- SYB1
- Synaptobrevin-1
- VAMP-1
UniProt编号 - P23763
UniProt汇总 FUNCTION: SwissProt: P23763 # Involved in the targeting and/or fusion of transport vesicles to their target membrane.
SIZE: 118 amino acids; 12902 Da
SUBUNIT: Interacts with VAPA and VAPB.
SUBCELLULAR LOCATION: Isoform 1: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass type IV membrane protein (By similarity). & Isoform 2: Cytoplasmic vesicle membrane; Single-pass type IV membrane protein (By similarity). & Isoform 3: Mitochondrion outer membrane; Single-pass type IV membrane protein.
TISSUE SPECIFICITY: Nervous system, skeletal muscle and adipose tissue.
SIMILARITY: SwissProt: P23763 ## Belongs to the synaptobrevin family. & Contains 1 v-SNARE coiled-coil homology domain.产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain frozen at -20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles. 包装信息 数量 100 µL
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