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merck millipore,默克密理博,MAB3306,Anti-MMP-3 Antibody, cross reacts w/hMMP-10, clone 55-2A4
产品名称：Anti-MMP-3 Antibody, cross reacts w/hMMP-10, clone 55-2A4
产品型号：MAB3306
This Anti-MMP-3 Antibody, cross reacts w/hMMP-10, clone 55-2A4 is validated for use in ELISA, WB, IH(P) for the detection of MMP-3.
merck millipore,默克密理博,MAB3306,Anti-MMP-3 Antibody, cross reacts w/hMMP-10, clone 55-2A4
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 Sh, H, Po, R WB, ELISA M Purified Monoclonal Antibody 描述 产品目录编号 MAB3306 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-MMP-3 Antibody, cross reacts w/hMMP-10, clone 55-2A4 Alternate Names - Proteoglycanase
- Stromelysin-1
- Transin
产品信息 格式 Purified 演示 Liquid in 0.01M Na-Phosphate buffer, pH 7.0, 125 mM NaCl, containing 2% protease free bovine serum albumin. 应用 应用 This Anti-MMP-3 Antibody, cross reacts w/hMMP-10, clone 55-2A4 is validated for use in ELISA, WB, IH(P) for the detection of MMP-3. 主要应用 - Western Blotting
- ELISA
应用说明 Immunoblotting (0.5 μg/mL)
Immunohistochemistry on paraffin-embedded tissues (5-10μg/mL, PLP fixation required, not recommended for traditional formalin fixation. Immunohistochemistry on fresh frozen sections (0.5 μg/mL)
ElA生物信息 免疫原品种 Human matrix metalloproteinase 3 (human MMP-3, stromelysin-1) from synovial cells. 表位 cross reacts w/hMMP-10 克隆 55-2A4 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Mouse 特异性 The antibody specifically reacts with precursor and active forms of human MMP-3. This is a purified mouse monoclonal antibody to human matrix metalloproteinase 3 (human MMP-3, stromelysin-1) from synovial cells. The antibody cross reacts 34% with human MMP-10. 同种型 IgG1κ 品种反应性 SheepHumanPigRat 抗体类型 Monoclonal Antibody Entrez基因编号 - NM_002422.3
Entrez基因汇总 Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades fibronectin, laminin, collagens III, IV, IX, and X, and cartilage proteoglycans. The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. 基因符号 - EC 3.4.24.17
- MMP3
- STR1
- Transin-1
- STMY
- MGC126102
- STMY1
- SL-1
- MGC126103
- MGC126104
- transin-1
- proteoglycanase
- MMP-3
- progelatinase
非反应性品种 - Rabbit
- Bovine
- Mouse
UniProt编号 - P08254
UniProt汇总 FUNCTION: SwissProt: P08254 # Can degrade fibronectin, laminin, gelatins of type I, III, IV, and V; collagens III, IV, X, and IX, and cartilage proteoglycans. Activates procollagenase.
COFACTOR: Binds 4 calcium ions per subunit. & Binds 2 zinc ions per subunit.
SIZE: 477 amino acids; 53977 Da
DOMAIN: SwissProt: P08254 The conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme.
SIMILARITY: Belongs to the peptidase M10A family. & Contains 4 hemopexin-like domains.产品使用声明 销售限制 This product is not available for sale in Japan. 使用声明 - Manufactured by Daiichi Fine Chemical Co., Ltd
- Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain frozen at -20°C in undiluted aliquots for up to 12 months. 包装信息 数量 100 µg
上一件merck millipore产品：merck millipore,默克密理博,SF-426,miR-143-3p; Human, Cyanine 3, RNA Detection Probe,SmartFlare
下一件merck millipore产品：merck millipore,默克密理博,MABF318,Anti-CD3ε (mouse) Antibody, PE/Cy5, clone 145-2C11
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