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merck millipore,默克密理博,MAB3132,Anti-Surfactant Protein D Antibody, lectin domain, clone IVF11
产品名称：Anti-Surfactant Protein D Antibody, lectin domain, clone IVF11
产品型号：MAB3132
This Anti-Surfactant Protein D Antibody, lectin domain, clone IVF11 is validated for use in ELISA, IH(P), WB for the detection of Surfactant Protein D.
merck millipore,默克密理博,MAB3132,Anti-Surfactant Protein D Antibody, lectin domain, clone IVF11
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 R, H WB, ELISA M Purified Monoclonal Antibody 描述 产品目录编号 MAB3132 Replaces MAB3130 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-Surfactant Protein D Antibody, lectin domain, clone IVF11 Alternate Names - SP-D
背景信息 Surfactant protein D is a Ca2+ dependent carbohydrate binding protein with a structure similar to other C-type mammalian lectins. Its molecular weight is 620 kDa under non-reducing conditions and 43 kDa under reducing conditions. The function of SP-D is not clearly defined. SP-D enhances the production of oxygen radicals in alveolar macrophages and regulates some actions of SP-A. 产品信息 格式 Purified 演示 Immunoglobulin purified from tissue culture supernatant. Lyophilized from buffer containing 5 mg/mL BSA and 0.09% sodium azide. 应用 应用 This Anti-Surfactant Protein D Antibody, lectin domain, clone IVF11 is validated for use in ELISA, IH(P), WB for the detection of Surfactant Protein D. 主要应用 - Western Blotting
- ELISA
应用说明 Immunohistochemistry on snap frozen or paraffin embedded tissue.
Suggested working dilution for fresh rat tissue is 1:400 and for fresh human tissue is 1:20. Fixation: acetone 5 min at 4°C, paraformaldehyde, paraffin. Tissue pretreatment: microwave treatment 2 x 5 min at 750 W for paraffin tissues.
Western blot
ELISA: as capture antibody
Optimal working dilutions must be determined by the end user.生物信息 免疫原品种 Purified rat surfactant protein D from bronchoalveolar lavage. 表位 lectin domain 克隆 IVF11 宿主 Mouse 特异性 MAB3132 recognizes an epitope localized in the lectin domain of rat surfactant protein D (SP-D). Reacts with alveolar type II cells, alveolar macrophages, types of Clara cells (in which SpD is highly concentrated), SP-A+ and SP-A-, and extracellular deposits. Alveolar type III cells are negative. No reaction on rat skin, colon, kidney or liver. SP-A cross reacitivity is typically evident at very low dilutions (1 to less than a few hundred) by ELISA. 同种型 IgG1κ 品种反应性 RatHuman 抗体类型 Monoclonal Antibody Entrez基因编号 - NM_003019.4
基因符号 - COLEC7
- SFTPD
- SP-D
- SFTP4
- PSPD
- PSP-D
UniProt编号 - P35247
UniProt汇总 FUNCTION: SwissProt: P35247 # Contributes to the lung's defense against inhaled microorganisms. May participate in the extracellular reorganization or turnover of pulmonary surfactant. Binds strongly maltose residues and to a lesser extent other alpha-glucosyl moieties.
SIZE: 375 amino acids; 37698 Da
SUBUNIT: Oligomeric complex of 4 set of homotrimers.
SUBCELLULAR LOCATION: Secreted, extracellular space.
PTM: The N-terminus is blocked. & Hydroxylation on proline residues within the sequence motif, GXPG, is most likely to be 4-hydroxy as this fits the requirement for 4-hydroxylation in vertebrates (By similarity).
SIMILARITY: SwissProt: P35247 ## Contains 1 C-type lectin domain. & Contains 1 collagen-like domain.
MISCELLANEOUS: Pulmonary surfactant consists of 90% lipid and 10% protein. There are 4 surfactant-associated proteins: 2 collagenous, carbohydrate-binding glycoproteins (SP-A and SP-D) and 2 small hydrophobic proteins (SP-B and SP-C).产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain lyophilized material at 2-8°C for up to 12 months from date of receipt. Reconstitute lyophilized material with 500 μL of sterile distilled water. After reconstitution, maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles. 包装信息 数量 200 µg
上一件merck millipore产品：merck millipore,默克密理博,324411,Dynamin Inhibitor II, MiTMAB - CAS 1119-97-7 - Calbiochem
下一件merck millipore产品：merck millipore,默克密理博,FCMAB205F,Milli-Mark™ Anti-CD68-FITC Antibody, clone KP1
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