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品种反应性 主要应用 宿主 格式 抗体类型 Rb, H, M IHC, FC, WB M Purified Monoclonal Antibody 描述 产品目录编号 CBL162 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-CD9 Antibody, clone MM2/57 Alternate Names - DRAP-27
- MRP-1
产品信息 格式 Purified 演示 The monoclonal is presented at a concentration of 100μg/1ml in phosphate buffered saline containing 10mM sodium azide and 1mg/ml bovine serum albumin. We recommend that each laboratory determine an optimum working titre for use in its particular application. 应用 应用 Anti-CD9 Antibody, clone MM2/57 detects level of CD9 & has been published & validated for use in FC, IP, WB, IH. 主要应用 - Immunohistochemistry
- Flow Cytometry
- Western Blotting
应用说明 Immunohistochemistry: Frozen sections of platelets, monocytes and pre-B cells with differential staining on lymphoid and epithelial tissues
Platelet inhibition and aggregation studies
Optimal working dilutions must be determined by the end user. the end user.生物信息 免疫原品种 Human platelet glycoprotein 克隆 MM2/57 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Mouse 特异性 This antibody reacts with a 25 kDa molecular weight band on gels of non-reduced platelet membranes and immunoprecipitates a similar band from Iodine125-labeled platelets. The antigen is expressed on eosinophils, granulocytes, monocytes and numerous stromal cells. This CD9 antigen belongs to the TM4 superfamily of cell surface proteins with the N- and C-terminals localized in the cytoplasm. 同种型 IgG2bκ 品种反应性 RabbitHumanMouse 抗体类型 Monoclonal Antibody Entrez基因编号 - NM_001769.2
Entrez基因汇总 The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It can modulate cell adhesion and migration and also trigger platelet activation and aggregation. In addition, the protein appears to promote muscle cell fusion and support myotube maintenance. 基因符号 - P24
- CD9
- Tspan-29
- MRP-1
- MIC3
- p24
- Tetraspanin-29
- BA2
- BTCC-1
- 5H9
- TSPAN29
- GIG2
- DRAP-27
纯化方法 Protein A purfied UniProt编号 - P21926
UniProt汇总 FUNCTION: SwissProt: P21926 # Involved in platelet activation and aggregation. Regulates paranodal junction formation. Required for gamete fusion. Involved in cell adhesion, cell motility and tumor metastasis.
SIZE: 228 amino acids; 25416 Da
SUBUNIT: Forms both disulfide-linked homodimers and higher homooligomers as well as heterooligomers with other members of the tetraspanin family. Associates with CR2/CD21 and with PTGFRN/CD9P1. Interacts directly with IGSF8.
SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
TISSUE SPECIFICITY: Expressed by a variety of hematopoietic and epithelial cells.
PTM: Protein exists in three forms with molecular masses between 22 and 27 kDa, and is known to carry covalently linked fatty acids. & Phosphorylated on tyrosine following B-cell activation.
SIMILARITY: SwissProt: P21926 ## Belongs to the tetraspanin (TM4SF) family.产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 1 year at 4°C from date of shipment 包装信息 数量 100 µg
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