merck millipore,默克密理博,654205,TNF-α, Human, Recombinant, E. coli

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Merck Millipore 默克密理愽

merck millipore,默克密理博,654205,TNF-α, Human, Recombinant, E. coli
产品名称：TNF-α, Human, Recombinant, E. coli
产品型号：654205

merck millipore,默克密理博,654205,TNF-α, Human, Recombinant, E. coli

描述
概述	Recombinant, human tumor necrosis factor-α expressed in E. coli. A cytokine produced primarily by activated macrophages that activates a variety of immune defense mechanisms by interactions with polymorphonuclear leukocytes, T cells, antibody-producing B lymphocytes, fibroblasts, and hematopoietic bone marrow cells. Activity is not species-specific. Induces apoptosis in human blood and bone marrow neutrophils and in endothelial cells. Increases the iNOS levels in vascular smooth muscle cells. Involved in pathophysiological processes of several chronic and acute diseases. Stimulates stress activated protein kinase (SAPK).
产品目录编号	654205
品牌系列	Calbiochem®
同义词	rhTNF-α, rh-Cachectin, Tumor Necrosis Factor-α

参考
参考	Merck Index 13, 9882. Tsuchida, H., et al. 1995. J. Immunol. 154, 2403. Westwick, J.K., et al. 1995. J. Biol. Chem. 270, 22689. Polunovsky, V.A., et al. 1994. Exp. Cell Res. 214, 584. Koide, M., et al. 1993. FEBS Lett. 318, 213. Vilcek, J., and Lee, T.H. 1991. J. Biol. Chem. 266, 7313.

生物信息
生物活性	ED₅₀ = 20-50 pg/ml as measured in a cytotoxicity assay with the TNF-α-susceptible murine L-929 cell line in the presence of Actinomycin D (Cat. No. 114666)
纯度	≥95% by SDS-PAGE

理化信息
污染物	Endotoxin: ≤0.1 ng/µg TNF-α
溶解度	Sterile, dH₂O

GHS安全信息
RTECS	MT6435000

储存和货运信息
货运代码	Ambient Temperature Only
毒性	Standard Handling
储存	≤ -70°C
无需冷冻	No
特殊指南	Following reconstitution, aliquot and freeze (-20°C or -70°C) for long-term storage or refrigerate (4°C) for short-term storage. Avoid freeze/thaw cycles of solutions. Stock solutions are stable for up to 3 months at -20°C or -70°C or up to 1 month at 4°C.

merck millipore,默克密理博,654205,TNF-α, Human, Recombinant, E. coli

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