merck millipore,默克密理愽
  • merck millipore,默克密理博,FCMAB205F,Milli-Mark™ Anti-CD68-FITC Antibody, clone KP1

  • merck millipore,默克密理博,FCMAB205F,Milli-Mark™ Anti-CD68-FITC Antibody, clone KP1

    产品名称：Milli-Mark™ Anti-CD68-FITC Antibody, clone KP1
    产品型号：FCMAB205F
    This Milli-Mark Anti-CD68-FITC Antibody, clone KP1 is validated for use in FC for the detection of CD68.

    merck millipore,默克密理博,FCMAB205F,Milli-Mark™ Anti-CD68-FITC Antibody, clone KP1

  • 产品介绍
  • merck millipore,默克密理博,FCMAB205F,Milli-Mark™ Anti-CD68-FITC Antibody, clone KP1

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    HFCMFITCMonoclonal Antibody
    描述
    产品目录编号 FCMAB205F
    商名
    • Milli-Mark
    描述 Milli-Mark™ Anti-CD68-FITC Antibody, clone KP1
    Alternate Names
    • Gp110
    • Macrosialin
    背景信息 CD68 is highly glycosylated lysosomal membrane protein with an Mr of 110,000. The CD68 protein belongs to a family of lysosomal glycoprotein (LGP)/plasma membrane shuttling proteins that play a role in endocytosis and/or lysosomal trafficking. CD68 is expressed strongly in cytoplasmic granules, and weakly on the surface of macrophages, monocytes, neutrophils, basophils, and NK cells. CD68 can also be found in the cytoplasm of non-hematopoietic tissues, especially the liver, and renal glomeruli, and tubules (Goyert, 1997).
    产品信息
    格式 FITC
    控制
    • Human Lymphocytes
    演示 Purified Mouse monoclonal IgG1 conjugated to FITC in 0.05M Tris-HCl buffer with 1% BSA, Sodium Azide at 0.097% at pH 7.2.
    应用
    应用 This Milli-Mark Anti-CD68-FITC Antibody, clone KP1 is validated for use in FC for the detection of CD68.
    主要应用
    • Flow Cytometry
    生物信息
    免疫原品种 Lysosomal fraction of human lung macrophages
    克隆 KP1
    宿主 Mouse
    特异性 Antibody recognizes Human CD68 antigen.
    同种型 IgG1κ
    品种反应性 Human
    Species Reactivity Note Tested and passed on Human.
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • NP_001035148
    Entrez基因汇总 This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms.
    纯化方法 Protein A Purified
    UniProt编号
    • P34810
    UniProt汇总 Could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. Binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin-bearing substrates or other cells.

    Highly expressed by blood monocytes and tissue macrophages. Also expressed in lymphocytes, fibroblasts and endothelial cells. Expressed in many tumor cell lines which could allow them to attach to selectins on vascular endothelium, facilitating their dissemination to secondary sites.
    产品使用声明
    质量保证 Evaluated by flow cytometry using human lymphocytes
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Maintain refrigerated at 2-8°C protected from light in undiluted aliquots for up to 6 months from date of receipt.
    包装信息
    数量 100 tests

    merck millipore,默克密理博,FCMAB205F,Milli-Mark™ Anti-CD68-FITC Antibody, clone KP1

上一件merck millipore产品：merck millipore,默克密理博,MAB3132,Anti-Surfactant Protein D Antibody, lectin domain, clone IVF11
下一件merck millipore产品：merck millipore,默克密理博,CBL162,Anti-CD9 Antibody, clone MM2/57


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