merck millipore,默克密理愽
  • merck millipore,默克密理博,MAB3075,Anti-G Protein Giα-1 Antibody, clone R4

  • merck millipore,默克密理博,MAB3075,Anti-G Protein Giα-1 Antibody, clone R4

    产品名称：Anti-G Protein Giα-1 Antibody, clone R4
    产品型号：MAB3075
    Anti-G Protein Giα-1 Antibody, clone R4 detects level of G Protein Giα-1 & has been published & validated for use in WB.

    merck millipore,默克密理博,MAB3075,Anti-G Protein Giα-1 Antibody, clone R4

  • 产品介绍
  • merck millipore,默克密理博,MAB3075,Anti-G Protein Giα-1 Antibody, clone R4

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    R, B, Gp, H, MWBMAscitesMonoclonal Antibody
    描述
    产品目录编号 MAB3075
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Anti-G Protein Giα-1 Antibody, clone R4
    产品信息
    格式 Ascites
    演示 Liquid ascites, containing sodium azide as a preservative.
    应用
    应用 Anti-G Protein Giα-1 Antibody, clone R4 detects level of G Protein Giα-1 & has been published & validated for use in WB.
    主要应用
    • Western Blotting
    应用说明 Western blot 1:500 - 1:2000.

    Labels a single protein band of 39 - 42 kDa in bovine and rat membranes.

    Optimal working dilutions must be determined by end user.
    生物信息
    免疫原品种 Rat brain G-proteins purified by the method of Sternweis and Robishaw (Sternweis & Robishaw, 1984).
    克隆 R4
    宿主 Mouse
    特异性 Gialpha-1. Strong reactivity with rat (100%), mouse (78%), bovine (74%) and guinea pig (48%). Slight reactivity with human (31%). Specificity confirmed by Western blot versus bovine Galphat, rat Goalpha, rat Gialpha-1, Gialpha-2, rat Gialpha-3, bovine Gsalpha, and murine GoalphaA and GoalphaB.
    同种型 IgG2b
    品种反应性 RatBovineGuinea PigHumanMouse
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • NM_002069.5
    Entrez基因汇总 Guanine nucleotide-binding proteins (G proteins) form a large family of signal-transducing molecules. They are found as heterotrimers made up of alpha, beta, and gamma subunits. Members of the G protein family have been characterized most extensively on the basis of the alpha subunit, which binds guanine nucleotide, is capable of hydrolyzing GTP, and interacts with specific receptor and effector molecules. The G protein family includes Gs (MIM 139320) and Gi, the stimulatory and inhibitory GTP-binding regulators of adenylate cyclase; Go, a protein abundant in brain (GNAO1; MIM 139311); and transducin-1 (GNAT1; MIM 139330) and transducin-2 (GNAT2; MIM 139340), proteins involved in phototransduction in retinal rods and cones, respectively (Sullivan et al., 1986 [PubMed 3092218]; Bray et al., 1987 [PubMed 3110783]). Suki et al. (1987) [PubMed 2440724] concluded that the human genome contains at least 3 nonallelic genes for alpha-i-type subunits of G protein; see, e.g, GNAI2 (MIM 139360), GNAI3 (MIM 139370), and GNAIH (MIM 139180).[supplied by OMIM]
    基因符号
    • Gi
    • GNAI1
    UniProt编号
    • P63096
    UniProt汇总 FUNCTION: SwissProt: P63096 # Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta-adrenergic stimuli.
    SIZE: 354 amino acids; 40361 Da
    SUBUNIT: G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site. Interacts with GPSM1 (By similarity).
    SIMILARITY: SwissProt: P63096 ## Belongs to the G-alpha family. G(i/o/t/z) subfamily.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Maintain at -20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.
    包装信息
    数量 100 µL

    merck millipore,默克密理博,MAB3075,Anti-G Protein Giα-1 Antibody, clone R4

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