merck millipore,默克密理愽
  • merck millipore,默克密理博,MAB1953,Anti-Integrin αV Antibody, clone P3G8

  • merck millipore,默克密理博,MAB1953,Anti-Integrin αV Antibody, clone P3G8

    产品名称：Anti-Integrin αV Antibody, clone P3G8
    产品型号：MAB1953
    Anti-Integrin αV Antibody, clone P3G8 is an antibody against Integrin αV for use in ELISA, FC, IP, IC, IH.

    merck millipore,默克密理博,MAB1953,Anti-Integrin αV Antibody, clone P3G8

  • 产品介绍
  • merck millipore,默克密理博,MAB1953,Anti-Integrin αV Antibody, clone P3G8

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    HIHC, ELISA, FC, ICCMPurifiedMonoclonal Antibody
    描述
    产品目录编号 MAB1953
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Anti-Integrin αV Antibody, clone P3G8
    Alternate Names
    • CD51
    产品信息
    格式 Purified
    应用
    应用 Anti-Integrin αV Antibody, clone P3G8 is an antibody against Integrin αV for use in ELISA, FC, IP, IC, IH.
    主要应用
    • Immunohistochemistry
    • ELISA
    • Flow Cytometry
    • Immunocytochemistry
    应用说明 Immunohistochemistry: 1:1,000. For use on acetone or paraformaldehyde fixed tissue

    Immunocytochemistry: 1:1,000. Will react with some lymphoid cell lines (B cells), many carcinoma and melanoma cell lines and osteosarcomas.

    Flow cytometry

    Immunoprecipitation

    FACS

    EIA

    Optimal working dilutions must be determined by end user.
    生物信息
    免疫原品种 UCLA P3 lung carcinoma cells
    克隆 P3G8
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Mouse
    特异性 Reacts with human alphaV integrin subunit and with all alphaV-containing integrin receptors.
    同种型 IgG1
    品种反应性 Human
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • NM_002210.2
    Entrez基因汇总 ITAGV encodes integrin alpha chain V. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The I-domain containing integrin alpha V undergoes post-translational cleavage to yield disulfide-linked heavy and light chains, that combine with multiple integrin beta chains to form different integrins. Among the known associating beta chains (beta chains 1,3,5,6, and 8; 'ITGB1', 'ITGB3', 'ITGB5', 'ITGB6', and 'ITGB8'), each can interact with extracellular matrix ligands; the alpha V beta 3 integrin, perhaps the most studied of these, is referred to as the Vitronectin receptor (VNR). In addition to adhesion, many integrins are known to facilitate signal transduction.
    基因符号
    • VNRA
    • ITGAV
    • DKFZp686A08142
    • MSK8
    • CD51
    UniProt编号
    • P06756
    UniProt汇总 FUNCTION: SwissProt: P06756 # The alpha-V integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and von Willebrand factor. They recognize the sequence R-G-D in a wide array of ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.
    SIZE: 1048 amino acids; 116038 Da
    SUBUNIT: Heterodimer of an alpha and a beta subunit. The alpha subunit is composed of an heavy and a light chain linked by a disulfide bond. Alpha-V associates with either beta-1, beta-3, beta-5, beta-6 or beta-8 subunit. Interacts with HIV-1 Tat.
    SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.
    SIMILARITY: SwissProt: P06756 ## Belongs to the integrin alpha chain family. & Contains 7 FG-GAP repeats.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Maintain at 2-8°C in undiluted aliquots for up to 6 months.
    包装信息
    数量 100 µg

    merck millipore,默克密理博,MAB1953,Anti-Integrin αV Antibody, clone P3G8

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