merck millipore,默克密理愽
  • merck millipore,默克密理博,MAB1911,Anti-Tenascin Antibody, type III repeats 1-3, clone 9F8

  • merck millipore,默克密理博,MAB1911,Anti-Tenascin Antibody, type III repeats 1-3, clone 9F8

    产品名称：Anti-Tenascin Antibody, type III repeats 1-3, clone 9F8
    产品型号：MAB1911
    This Anti-Tenascin Antibody, type III repeats 1-3, clone 9F8 is validated for use in ELISA, WB, IC, IH for the detection of Tenascin.

    merck millipore,默克密理博,MAB1911,Anti-Tenascin Antibody, type III repeats 1-3, clone 9F8

  • 产品介绍
  • merck millipore,默克密理博,MAB1911,Anti-Tenascin Antibody, type III repeats 1-3, clone 9F8

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    HIHC, ELISA, WB, ICCMPurifiedMonoclonal Antibody
    描述
    产品目录编号 MAB1911
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Anti-Tenascin Antibody, type III repeats 1-3, clone 9F8
    产品信息
    格式 Purified
    演示 Liquid in 0.02 M phosphate, 0.25 M Sodium Chloride pH 7.6, with 0.1% Sodium Azide.
    应用
    应用 This Anti-Tenascin Antibody, type III repeats 1-3, clone 9F8 is validated for use in ELISA, WB, IC, IH for the detection of Tenascin.
    主要应用
    • Immunohistochemistry
    • ELISA
    • Western Blotting
    • Immunocytochemistry
    应用说明 Immunohistochemistry at 2 μg/mL on tissues fixed with cold acetone

    Immunocytochemistry at 2 μg/mL on U251 cells

    Immunoblotting (Western) at 2 μg/mL to detect whole tenascin under reducing conditions

    ELISA: 2 x 10-10 M endpoint dilution

    Affinity constant Kd= 6.37 x 10-9

    Final working dilutions must be determined by end user.
    生物信息
    免疫原品种 Purified human tenascin
    表位 type III repeats 1-3
    克隆 9F8
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Mouse
    特异性 Binds to a recombinant fragment of human tenascin containing the fibronectin type III repeats, numbers 1-3.
    同种型 IgG1κ
    品种反应性 Human
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • NM_000632.3
    Entrez基因汇总 This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Some integrin alpha M proteins contain an inserted amino acid (Q, between AA positions 499 and 500) resulting from a 3bp shift in a splice acceptor that inserts the codon CAG; receptors with or without the extra amino acid are functionally indistinguishable
    基因符号
    • MAC-1
    • ITGAM
    • MO1A
    • CD11b
    • CR3A
    • MAC1A
    • CD11B
    • MGC117044
    UniProt编号
    • P11215
    UniProt汇总 FUNCTION: SwissProt: P11215 # Integrin alpha-M/beta-2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin alpha-M/beta-2 is also a receptor for fibrinogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain.
    SIZE: 1152 amino acids; 127179 Da
    SUBUNIT: Heterodimer of an alpha and a beta subunit. Alpha-M associates with beta-2.
    SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.
    TISSUE SPECIFICITY: Predominantly expressed in monocytes and granulocytes.
    DOMAIN: SwissProt: P11215 The integrin I-domain (insert) is a VWFA domain. Integrins with I-domains do not undergo protease cleavage.
    SIMILARITY: Belongs to the integrin alpha chain family. & Contains 7 FG-GAP repeats. & Contains 1 VWFA domain.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Store at 2 and 8°C for up to 6 months.
    包装信息
    数量 100 µg

    merck millipore,默克密理博,MAB1911,Anti-Tenascin Antibody, type III repeats 1-3, clone 9F8

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